Vernakalant

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Vernakalant
File:Vernakalant.svg
Systematic (IUPAC) name
(3R)-1-{(1R,2R)-2-[2-(3,4-dimethoxyphenyl)
ethoxy]cyclohexyl}pyrrolidin-3-ol
Clinical data
Routes of
administration
Intravenous, oral
Identifiers
CAS Number 794466-70-9 748810-28-8 (HCl)
ATC code none
PubChem CID 9930049
Chemical data
Formula C20H31NO4
Molar mass 349.464 g/mol[[Script error: No such module "String".]]
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Vernakalant (INN; codenamed RSD1235, proposed tradenames Kynapid or Brinavess) is an investigational drug under regulatory review for the acute conversion of atrial fibrillation.

It is being developed by Cardiome Pharma Corp.

On December 11, 2007, the Cardiovascular and Renal Drugs Advisory Committee of the US Food and Drug Administration voted to recommend the approval of vernakalant.[1]

An oral formulation is currently undergoing Phase II clinical studies.

References

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  1. "FDA Advisory Committee Recommends Approval of Kynapid for Acute Atrial Fibrillation". Drugs.com. Retrieved 2008-03-15.