Voacangine
From Self-sufficiency
| Voacangine | |
|---|---|
| File:Voacangine.svg | |
| 12-methoxyibogamine- 18-carboxylic acid methyl ester | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 510-22-5 |
| PubChem | 261793 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C22H28N2O3 |
| Molar mass | 368.47 g/mol |
| Melting point |
136–137 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Voacangine (12-methoxyibogamine-18-carboxylic acid methyl ester) is an alkaloid found predominantly in the rootbark of the Voacanga africana tree, as well as in other plants such as Tabernanthe iboga, Tabernaemontana africana, Trachelospermum jasminoides and Ervatamia yunnanensis.[1][2][3][4] It is an iboga alkaloid which commonly serves as a precursor for the semi-synthesis of ibogaine.[5] It has also been demonstrated in animals to have similar anti-addictive properties to ibogaine itself.[6]
See also
References
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- ↑ Patel MB, Miet C, Poisson J. Alkaloids of some African Tabernaemontana. (French) Annales Pharmaceutiques Francaises. 1967 May;25(5):379-84. PMID 5611538
- ↑ Fatima T, Ijaz S, Crank G, Wasti S. Indole Alkaloids from Trachelospermum jasminoides. Planta Medica. 1987 Feb;53(1):57-9. PMID 17268963
- ↑ Liu G, Liu X, Feng XZ. Ervayunine: a new indole alkaloid from Ervatamia yunnanensis. Planta Medica. 1988 Dec;54(6):519-21. PMID 3212080
- ↑ Jenks CW. Extraction studies of Tabernanthe iboga and Voacanga africana. Natural Product Letters. 2002 Feb;16(1):71-6. PMID 11942686
- ↑ USA Patent No. 2813873 "Derivatives of the Ibogaine Alkaloids"
- ↑ Tsing Hua. Antiaddictive indole alkaloids in Ervatamia yunnanensis and their bioactivity. Academic Journal of Second Military Medical University. January 28, 2006.
