View source for Gingerol

{{chembox
|   Name = Gingerol
|   ImageFile = Gingerol.png
|   ImageSize = 200px
|   ImageName = Gingerol
|   IUPACName = (''S'')-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
| Section1 = {{Chembox Identifiers
|   CASNo = 23513-14-6
|   SMILES = O=C(C[C@@H](O)CCCCC)<br />CCC1=CC=C(O)C(OC)=C1
  }}
| Section2 = {{Chembox Properties
|   Formula = C<sub>17</sub>H<sub>26</sub>O<sub>4</sub>
|   MolarMass = 294.38 g/mol
|   Density = 
|   MeltingPt = 30-32 °C
|   BoilingPt = 
  }}
}}

'''Gingerol''', or sometimes [6]-gingerol, is the active constituent of fresh [[ginger]].  Chemically, gingerol is a relative of [[capsaicin]], the compound that gives [[chile pepper]]s their spiciness.  It is normally found as a pungent yellow oil, but also can form a low-melting crystalline solid.

Cooking ginger transforms gingerol into [[zingerone]], which is less pungent and has a spicy-sweet aroma.

==Physiological effects==
Gingerol may reduce nausea caused by motion sickness or pregnancy<ref>{{Cite pmid|10793599}}</ref> and may also relieve migraine.<ref>{{Cite pmid|2214812}}</ref>

[6]-Gingerol  has been used to induce a [[suspended animation]]-like [[hypothermia|hypothermic]] state in rats <ref>{{Cite pmid|18295202}}</ref>.

Gingerol seems to be effective in an animal model of [[rheumatoid arthritis]].<ref>{{cite web |url=http://www.ncbi.nlm.nih.gov/pubmed/19216559 |title=Comparative effects of two gingerol-containing Zingiber officinale extracts on experimental rheumatoid arthritis. }}</ref>

Ginger or gingerol have been evaluated in a large number of clinical studies.<ref>{{cite web |url=http://www.jivaresearch.org/Ginger.php |title=Ginger Clinical Studies }}</ref>

==References==
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[[Category:Phenols]]
[[Category:Ketones]]
[[Category:Pungent flavors]]
[[Category:Phenol ethers]]
[[Category:Alcohols]]
[[Category:Ginger]]

[[cs:Gingerol]]
[[de:Gingerol]]
[[fr:Gingerol]]
[[Category:2Fix]]