View source for Metaraminol

{{drugbox
| verifiedrevid = 305804190
| IUPAC_name = (1''R'',2''S'')-3-[-2-amino-1-hydroxy-propyl]phenol
| image = Metaraminol Structural Formulae.png
| CASNo_Ref = {{cascite}}
| CAS_number = 54-49-9
| ATC_prefix = C01
| ATC_suffix = CA09
| PubChem = 5906
| DrugBank = APRD00555
| C = 9 | H = 13 | N = 1 | O = 2
| molecular_weight = 167.205 g/mol
| bioavailability = n/a
| protein_bound = ~45%
| metabolism = [[Liver|Hepatic]]
| elimination_half-life = 
| excretion = 
| pregnancy_AU = C
| pregnancy_US = C
| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
| legal_UK = POM
| legal_US = <!-- OTC / Rx-only -->
| routes_of_administration = [[Intravenous therapy|Intravenous]]
}}

'''Metaraminol''' ([[International Nonproprietary Name|INN]], trade name '''Aramine''') is a potent [[sympathomimetic amine]] used in the prevention and treatment of [[hypotension]], particularly as a complication of [[anesthesia]].
It is an [[adrenergic receptor|α<sub>1</sub>-adrenergic receptor]] [[agonist]] with some β effect.

Metaraminol is also used in the treatment of [[priapism]]. Although not approved for this use, it appears to be effective.<ref name = McDonald>{{cite journal | author = McDonald M, Santucci R | title = Successful management of stuttering priapism using home self-injections of the alpha-agonist metaraminol. | journal = Int Braz J Urol | volume = 30 | issue = 2 | pages = 121–2 | year = 2004 | pmid = 15703094 | doi = 10.1590/S1677-55382004000200007}}</ref><ref name = Koga>{{cite journal | author = Koga S, Shiraishi K, Saito Y | title = Post-traumatic priapism treated with metaraminol bitartrate: case report. | journal = J Trauma | volume = 30 | issue = 12 | pages = 1591–3 | year = 1990 | pmid = 2258979 | doi = 10.1097/00005373-199012000-00029}}</ref><ref name = Block>{{cite journal | author = Block T, Sturm W, Ernst G, Staehler G, Schmiedt E | title = [Metaraminol in therapy of various forms of priapism] | journal = Urologe A | volume = 27 | issue = 4 | pages = 225–9 | year = 1988 | pmid = 3140463}}</ref>

== See also ==
* [[Gepefrine]]

== References ==
{{Reflist|2}}


{{Adrenergics}}
{{Phenethylamines}}

[[Category:Alpha-adrenergic agonists]]
[[Category:Amphetamines]]
[[Category:Cardiac stimulants]]
[[Category:Phenols]]


{{cardiovascular-drug-stub}}

[[de:Metaraminol]]
[[pt:Metaraminol]]
[[Category:2Fix]]