Metaraminol

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Metaraminol
File:Metaraminol Structural Formulae.png
Systematic (IUPAC) name
(1R,2S)-3-[-2-amino-1-hydroxy-propyl]phenol
Clinical data
Pregnancy
category
  • AU: C
  • US: C (Risk not ruled out)
Routes of
administration
Intravenous
Legal status
Legal status
  • UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability n/a
Protein binding ~45%
Metabolism Hepatic
Identifiers
CAS Number 54-49-9
ATC code C01CA09 (WHO)
PubChem CID 5906
DrugBank APRD00555
Chemical data
Formula C9H13NO2
Molar mass 167.205 g/mol[[Script error: No such module "String".]]
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Metaraminol (INN, trade name Aramine) is a potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. It is an α1-adrenergic receptor agonist with some β effect.

Metaraminol is also used in the treatment of priapism. Although not approved for this use, it appears to be effective.[1][2][3]

See also

References

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de:Metaraminol pt:Metaraminol
  1. McDonald M, Santucci R (2004). "Successful management of stuttering priapism using home self-injections of the alpha-agonist metaraminol". Int Braz J Urol. 30 (2): 121–2. doi:10.1590/S1677-55382004000200007. PMID 15703094. 
  2. Koga S, Shiraishi K, Saito Y (1990). "Post-traumatic priapism treated with metaraminol bitartrate: case report". J Trauma. 30 (12): 1591–3. doi:10.1097/00005373-199012000-00029. PMID 2258979. 
  3. Block T, Sturm W, Ernst G, Staehler G, Schmiedt E (1988). "[Metaraminol in therapy of various forms of priapism]". Urologe A. 27 (4): 225–9. PMID 3140463.