Difference between revisions of "Mantle zone"

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Latest revision as of 20:26, 21 September 2010

Germinal centre
File:Keimzentrum.jpg
Image labeled in German, but "Mantel-zone" visible near center.

The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]

It is also known as the "corona".[2]

It contains transient lymphocytes.[3]

It is the location of the lymphoma in mantle cell lymphoma.

Pathology

File:Castleman disease - intermed mag.jpg
Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.

Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e. Mantle cell lymphoma.

References

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External links

  1. http://teaching.path.cam.ac.uk/partIB_pract/P05/
  2. http://www3.umdnj.edu/histsweb/lab12/lab12nodes.html
  3. http://www.dartmouth.edu/~nlevy/levylecture.html