Difference between revisions of "Linsidomine"
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Latest revision as of 15:49, 19 September 2010
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| Systematic (IUPAC) name | |
|---|---|
|
5-imino-3-morpholin-4-yl-5H-1,2,3-oxadiazol-3-ium-2-ide | |
| Identifiers | |
| ATC code | C01DX18 (WHO) |
| PubChem | CID 5219 |
| Chemical data | |
| Formula | C6H10N4O2 |
| Molar mass | 170.17 g/mol[[Script error: No such module "String".]] |
Linsidomine is a vasodilator. Linsidomine (SIN-1) is a metabolite of the antianginal drug molsidomine and acts by releasing NO from the endothelial cells nonenzymatically. It also hyperpolarizes the cell membrane through influencing the sodium-potassium pump and thereby rendering it less responsive to adrenergic stimulation ). Linsidomine injection at a dose of 1 mg produces usable erection in about 70% of patients and full erection in up to 50% of patients . Linsidomine does not appear to be associated with priapism .
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