AEZS-108
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Revision as of 23:43, 15 September 2010 by WereSpielChequers (Talk) (Adding category Category:Drugs; removed {{uncategorized}} (using HotCat))
AEZS-108 (previously AN-152) consists of [D-Lys(6)]LHRH linked to doxorubicin.
It is an experimental targeted therapy for various cancers (ovarian, endometrial, breast, bladder, prostate) that express LHRH receptor. The US FDA have granted it orphan drug status.
Promising results have been reported from a phase II clinical trial for ovarian cancer.[1]
It is also in a phase II trial for endometrial cancer.
References
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