Methscopolamine

Methscopolamine

File:Methscopolamine.png
Systematic (IUPAC) name
(1R,2S,4R,5S,7R)-{[(2R)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane
Identifiers
CAS Number	155-41-9
ATC code	none
PubChem	CID 441342
DrugBank	APRD00314
Chemical data
Formula	C18H24NO4
Molar mass	318.388 g/mol[[]]
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Methscopolamine, usually provided as a bromide salt (Pamine), is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this anymore. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold and allergy medications (Extendryl, AlleRx, Rescon).

Methscopolamine, a methylated derivative of scopolamine, is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine. Its mechanism of action involves blocking the muscarinic acetylcholine receptors.