Salicylhydroxamic acid
From Self-sufficiency
| File:Salicylhydroxamic acid.png | |
| Systematic (IUPAC) name | |
|---|---|
|
2-Hydroxybenzenecarbohydroxamic acid | |
| Identifiers | |
| CAS Number | 89-73-6 |
| ATC code | none |
| PubChem | CID 66644 |
| Chemical data | |
| Formula | C7H7NO3 |
| Molar mass | 153.14 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Salicylhydroxamic acid (SHA) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965). It is also a trypanocidal agent.
When administered orally, it is metabolised to salicylamide which exerts analgesic, antipyretic and antiinflammatory effects.
Salicylhydroxamic acid is a common ligand utilized in the synthesis of metallacrowns.
See also
References
- W. Fishbein and P. Carbone, J Biol Chem. 1965 Jun; 240:2407-14.
| 40px | This drug article relating to the genito-urinary system is a stub. You can help ssf by expanding it. |
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