Necitumumab

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Necitumumab
Monoclonal antibody
Type Whole antibody
Source Template:Infobox drug/mab source
Target EGFR
Identifiers
CAS Number 906805-06-9
ATC code none
Chemical data
Formula C6436H9958N1702O2020S42
Molar mass 144.84 kDa[[Script error: No such module "String".]]
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Necitumumab (proposed INN) is a monoclonal antibody and an antineoplastic. It binds to the epidermal growth factor receptor (EGFR).[1] As of October 2009, two Phase III clinical trials are planned to investigate its effects on non-small cell lung carcinoma.[2][3]

References

  1. International Nonproprietary Names for Pharmaceutical Substances (INN, prepublication copy), World Health Organization.
  2. ClinicalTrials.gov NCT00981058 Squamous Non-Small Cell Lung Cancer (NSCLC) Treatment With the Inhibitor of Epidermal Growth Factor Receptor (EGFR) (SQUIRE)
  3. ClinicalTrials.gov NCT00982111 NonSquamous Non-Small Cell Lung Cancer Treatment With the Inhibitor of Epidermal Growth Factor Receptor (INSPIRE)