Desmethoxyyangonin
From Self-sufficiency
| Desmethoxyyangonin | |
|---|---|
| File:Desmethoxyyangonin.svg | |
| 4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one | |
| Other names 5,6-Dehydrokawain 4-methoxy-6-[(E)-2-phenylvinyl]-2-pyranone | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 1952-41-6 |
| PubChem | 5273621 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C14H12O3 |
| Molar mass | 228.24 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Desmethoxyyangonin or 5,6-dehydrokawain is one of the six major kavalactones found in the Piper methysticum (kava) plant.
Pharmacology
Desmethoxyyangonin is a reversible inhibitor of monoamine oxidase B (MAO-B). It is able to increase dopamine levels in the nucleus accumbens. This may be the reason for the euphoria from Kava consumption.
Desmethoxyyangonin has marked activity on the induction of CYP3A23.[1]
References
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