Leu-enkephalin
From Self-sufficiency
| Leu-enkephalin | |
|---|---|
| File:Leu-enkaphalin.png | |
| (2R)-2-[[(2R)-2-[[2-[[2-[[(2R)-2-amino-3- (4-hydroxyphenyl)propanoyl]amino]acetyl] amino]acetyl]amino]-3-phenylpropanoyl] amino]-4-methylpentanoic acid | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 58822-25-6 |
| PubChem | 10415290 |
| IUPHAR ligand | 1613 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C28H37N5O7 |
| Molar mass | 555.62268 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Leu-enkephalin is an endogenous opioid peptide neurotransmitter found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine.
Leu-Enkephalin is a peptide whose sequence is: Tyr - Gly - Gly - Phe - Leu. It produces pharmacological effects at both the mu and delta opioid receptors, showing selectivity for the delta receptor.
It has a much higher selectivity for δ opioid receptors than μ receptors, and has little to no effect on κ opioid receptors.
| 40px | This biochemistry article is a stub. You can help ssf by expanding it. |
