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...rasite cell autodigestion. In essence, the parasite cell drowns in its own metabolic products.<ref>{{cite journal | author = Hempelmann E.| title = Hemozoin bi

...that could increase the risk of [[lactic acidosis]], including [[kidney]] disorders ([[creatinine]] levels over 150 μmol/l,<ref name="Jones2003">{{vcite journ ...ournal |author=Towler MC, Hardie DG |title=AMP-activated protein kinase in metabolic control and insulin signaling |journal=Circ Res |volume=100 |issue=3 |pages

...PE, Lynd LD |title=Selective serotonin-reuptake inhibitor-induced movement disorders |journal=Ann Pharmacother |volume=32 |issue=6 |pages=692–8 |year=1998 |pm ...e=Classification Trees Distinguish Suicide Attempters in Major Psychiatric Disorders: A Model of Clinical Decision Making |journal=J Clin Psychiatry |volume= |i

*[[metabolic acidosis]] (a severe condition with a more acidic blood than normal) *severe disorders in peripheral arterial circulation

...ociety’s 10th International Congress of Parkinson's Disease and Movement Disorders on November 1, 2006, in Kyoto, Japan.]</ref> It was named dopamine because ...e controls the flow of information from other areas of the brain. Dopamine disorders in this region of the brain can cause a decline in [[neurocognitive]] funct

...m, creating a hyperchloremic metabolic acidosis.<ref>Renal and Electrolyte Disorders Schrier 1976: page 89</ref> This effect can also be used for therapeutic co ...elerates this process by leading to a more rapid renal bicarbonate loss ([[metabolic acidosis]]).

...-176}}</ref> This can cause a major problem with the [[hyperkalemia]] of [[metabolic shock]] from surgery. Cortisol reduces [[calcium]] absorption in the intest |+ THE DISORDERS OF CORTISOL SECRETION<!-- -->

...{Citation needed|date=January 2009}} In the presence of pain and the other disorders for which morphine is indicated, a combination of psychological and physiol ...getfulness), low self-esteem, confusion, paranoia, and other psychological disorders. The psychological dependence on morphine can, and usually does, last a lif

...y weight and condition being treated. For the elderly or people with liver disorders, initial dose is at the low end of the range, with the dose being increased * Liver disorders

...[[cerebral edema|swelling in the brain]], [[coagulopathy|blood coagulation disorders]], [[rhabdomyolysis|muscle breakdown]] (rhabdomyolysis), and [[kidney failu ...habdomyolysis]], [[hyperthermia]], or low blood pressure may be required. Metabolic acidosis is treated by administering [[sodium bicarbonate]].<ref>{{cite jou

...ole (botany)|petiole]]s, contain [[oxalic acid]] [[salt]]s, causing kidney disorders, convulsions, coma. Rarely fatal. ...Well-known as a livestock poison in South Africa; this plant contains the metabolic poison [[Sodium fluoroacetate|fluoroacetic acid]].

...frequently than acquired nystagmus. It can be insular or accompany other disorders (such as micro-ophthalmic anomalies or [[Down's Syndrome]]). Congenital ny ====Toxic/metabolic====

...iron-poor environments and have evolved to use different elements in their metabolic processes, such as manganese instead of iron for catalysis, or [[hemocyanin ...ewhere, which can cause significant adverse effects, including [[coma]], [[metabolic acidosis]], [[Shock (circulatory)|shock]], [[liver failure]], [[coagulopath

..., such as ''[[Neurospora crassa]]''.<ref name=Fahey/> Although the exact [[metabolic pathway]] is not clear, it is known that the imidazole ring is supplied by ...up>}}</ref> Mutants of this transporter are associated with the autoimmune disorders [[rheumatoid arthritis]] and [[Crohn's disease]].<ref name=Schomig>{{cite j

...=Axelrod YK, Diringer MN |title=Temperature management in acute neurologic disorders |journal=Neurol Clin |volume=26 |issue=2 |pages=585–603, xi |year=2008 |m ...=Axelrod YK, Diringer MN |title=Temperature management in acute neurologic disorders |journal=Neurol Clin |volume=26 |issue=2 |pages=585–603, xi |year=2008 |m

....<ref name="Toxicology2002-omaye">{{cite journal | author=Omaye ST | title=Metabolic modulation of carbon monoxide toxicity | journal=Toxicology | year=2002 | p ...isease]] and other hematological disorders, [[barometric pressure]], and [[metabolic rate]].<ref>{{cite web|url=http://www.lungusa.org/site/pp.asp?c=dvLUK9O0E&b

...Manganese poisoning has been linked to impaired motor skills and cognitive disorders.<ref>{{cite web| url=http://rais.ornl.gov/tox/profiles/mn.html|publisher=Oa ...= 10.1023/A:1021970120965|year = 2002|author = Normandin, Louise|journal = Metabolic Brain Disease|volume = 17|pages = 375|pmid = 12602514|last2 = Hazell|first2

...ased, which might form reactive oxygen species and oxidative stress. These metabolic interferences lead to death from multi-system [[organ failure]], probably f ...days.<ref>{{cite book|title=The Psychiatric, Psychogenic ans Somatopsychic Disorders Handbook |location=New Hyde Park, NY|publisher=Medical Examination Publishi

{{cquote|Some of the abnormalities include metabolic exhaustion of the hair cells, structural changes and degeneration of struct ...apies look hopeful (National Institute on Deafness and Other Communication Disorders [NIDCD], 2006).

...is classified based on the [[etiology]] of the disturbance (respiratory or metabolic) and the direction of change in pH (acidosis or alkalosis). This yields the | [[metabolic acidosis]] || down || down || respiratory

...rders, known as the ''[[porphyria]]s'' that are characterized by errors in metabolic pathways of heme synthesis. King [[George III of the United Kingdom]] was p | title = Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management

* Agamanolis DP. Metabolic and toxic disorders. In: Prayson R, editor. Neuropathology: a volume in the foundations in dia

...Kussmaul respiration</ref> || [[Adolph Kussmaul]] || endocrinology || [[metabolic acidosis]] || ||laboured deep breathing with normal or reduced frequency ...al medicine]] ||pernicious anaemia, coeliac disease, other malabsorption disorders || ||B12 radioassay; rare

* [[Mental deficiency-epilepsy-endocrine disorders]] * [[Metabolic acidosis]]

=== Metabolic === ==Complex disorders==

*[[Adenoid disorders]] *[[Adrenal disorders]]

'''More common disorders''' | Adrenal gland disorders <br><small>''see'' [[21-hydroxylase deficiency]] </small> || ||

==Skeletal and muscular disorders== ...forelimbs.<ref>{{cite web | title = Panosteitis | work = Canine Inherited Disorders Database | publisher = University of Prince Edward Island | year = 1998 | u

...ndromes are caused by malnutrition, by failure to absorb phosphate, and by metabolic syndromes which draw phosphate from the blood or pass too much of it into t ...which carries oxygen and nutrients to cells, and [[carbon dioxide]] and [[Metabolic waste|waste]]s in the opposite direction. Also, the [[digestive system]], w

** [[Phagocyte disorders]] ** [[Myeloproliferative disorders]]

...xia sensing. This enzyme is activated during times of net energy usage and metabolic stress, including hypoxia. AMPK has a number of targets and it appears that Arterial [[acidosis]] (either [[metabolic acidosis|metabolic]] or from altered [[respiratory acidosis|P<small>CO₂</small>]])

...occurs spontaneously. [[Genetic disorders]], and [[teratogen]]s (viruses, metabolic imbalance, and industrial or pharmacological agents) have been associated a

...ogically as its coenzyme A ester, [[propionyl-CoA]], from the [[metabolism|metabolic]] breakdown of fatty acids containing [[odd number]]s of [[carbon]] atoms, In propanoic acidemia, propionate acts as a metabolic toxin in liver cells by accumulating in mitochondria as propionyl-CoA and i

...eing effective treating an often drug-induced set of neurological movement disorders known as [[dystonia]].<ref name=Snider1985/> In one study, five out of five ''[[Cannabis]]'', produces CBD-[[carboxylic acid]] through the same [[metabolic pathway]] as THC, until the last step, where CBDA synthase performs catalys

...in the fourth edition of the [[Diagnostic and Statistical Manual of Mental Disorders]] (DSM-IV). Nevertheless, treatment options have been made available for t ...g [[positron emission tomography]] (PET) and fMRI techniques have reported metabolic alterations within frontal regions of marijuana smokers <ref name=Gruber200

...unique in that they do not always exhibit outward symptoms. Defining the disorders becomes difficult and so neuroproteomics is a step in the right direction o ...proach dedicated to studying proteomic changes in the field of psychiatric disorders, particularly substance-and drug-abuse neurotoxicity.

The short length of action of hydromorphone and other metabolic factors mean that the abstinence syndrome (withdrawal) is brief but intense ...avoiding or reducing first-pass hepatic metabolism, rapid action and short metabolic and elimination half-life and other chemical characteristics including high

...lizers (~10% of the Caucasian population) have a reduced capacity for this metabolic pathway, and so might receive a reduced analgesic benefit from the drug. Ho ...Some less common side effects are [[allergy|allergic reaction]], [[blood]] disorders, changes in mood, racing heartbeat, mental fogginess, [[anxiety]], [[lethar

[[File:GHB metabolic pathway.svg|thumb|center|600px|Metabolic pathway of GHB.]] Also note that both of the metabolic breakdown pathways shown for GHB can run in either direction, depending on