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• Sodium nitrite
  ...arbocations that react with biological [[nucleophile]]s (such as DNA or an enzyme) in the cell. [[Category:Corrosion inhibitors]]
  21 KB (3,046 words) - 16:45, 27 September 2010
• Ciprofloxacin
  ...=PDF|quote=Although the current quinolones are not considered to be potent inhibitors of eucaryotic topoisomerases, some effects on these and other enzymes invol ...comparison of active site binding of 4-quinolones and novel flavone gyrase inhibitors to DNA gyrase |journal=Adv Exp Med Biol. |volume=390 |pages=59–69 |year=1
  88 KB (11,930 words) - 16:46, 27 September 2010
• Methylene blue
  ...[serotonin syndrome]], if combined with any [[selective serotonin reuptake inhibitors]] (SSRIs) or other serotonin reuptake inhibitor (e.g., [[duloxetine]], [[si ...monophosphate ([[Cyclic guanosine monophosphate|cGMP]]) by inhibiting the enzyme [[guanylate cyclase]]: this action results in reduced responsiveness of ves
  27 KB (3,650 words) - 16:46, 27 September 2010
• Metformin
  ...he United States, trade name ''Glucovance''), the [[dipeptidyl peptidase-4 inhibitors|dipeptidyl peptidase-4 inhibitor]] [[sitagliptin]] (trade name ''Janumet'') .../ref> Metformin activates [[AMP-activated protein kinase]] (AMPK), a liver enzyme that plays an important role in insulin signaling, whole body energy balanc
  66 KB (8,976 words) - 16:47, 27 September 2010
• Valproic acid
  Valproic acid is an [[Enzyme inhibitor|inhibitor]] of the [[enzyme]] [[histone deacetylase 1]] (HDAC1), hence it is a [[histone deacetylase in ...ally as often as once a week and then once every 2 months. Temporary liver enzyme increase has been reported in 20% of cases during the first few months of t
  25 KB (3,328 words) - 16:47, 27 September 2010
• Fluoxetine
  ...A, Wong DT |title=A note on the discovery of selective serotonin reuptake inhibitors |journal=Life Sci |volume=61 |issue=12 |pages=1203 |year=1997 |pmid=9315511 ...ey CF |title=Extrapyramidal reactions and the selective serotonin-reuptake inhibitors |journal=Ann Pharmacother |volume=31 |issue=12 |pages=1481–9 |year=1997 |
  52 KB (7,168 words) - 16:47, 27 September 2010
• Aspirin
  ...es, although they all have similar effects and most have inhibition of the enzyme [[cyclooxygenase]] as their [[nonsteroidal anti-inflammatory drugs#Mechanis ...er NSAIDs (such as [[diclofenac]] and [[ibuprofen]]), which are reversible inhibitors.
  78 KB (10,918 words) - 16:52, 27 September 2010
• Omeprazole
  Proton pump inhibitors may be associated with a greater risk of hip fractures,<ref name="JAMA">{{c | title=Use of proton pump inhibitors and risk of osteoporosis-related fractures
  17 KB (2,299 words) - 09:15, 5 September 2010
• Enalapril
  ...r of the group of ACE inhibitors known as the dicarboxylate-containing ACE inhibitors. ...hich aided in the development of subsequent [[carboxylate]]-containing ACE inhibitors.
  5 KB (725 words) - 16:48, 27 September 2010
• Dopamine
  ...st by the hydroxylation of the amino acid [[L-tyrosine]] to L-DOPA via the enzyme tyrosine 3-monooxygenase, also known as [[tyrosine hydroxylase]], and then ...rboxylase|dopa decarboxylase]]), such as [[carbidopa]] or [[benserazide]]. Inhibitors of alternative metabolic route for dopamine by [[catechol-O-methyl transfer
  48 KB (6,470 words) - 16:48, 27 September 2010
• Ibuprofen
  ...tory drugs such as ibuprofen work by [[enzyme inhibitor|inhibiting]] the [[enzyme]] [[cyclooxygenase]] (COX), which converts [[arachidonic acid]] to [[Prosta ...hor=Kakuta H, Zheng X, Oda H, ''et al.'' |title=Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage.
  29 KB (3,955 words) - 22:17, 21 September 2010
• Zidovudine
  ...on the viral enzyme [[reverse transcriptase]]. Reverse transcriptase is an enzyme that retroviruses, including HIV, utilize to replicate themselves. Scientis ...urnal | author=De Clercq E | title=HIV resistance to reverse transcriptase inhibitors. | journal=Biochem Pharmacol | volume=47 | issue=2 | pages=155–69 | year=
  21 KB (3,049 words) - 16:51, 27 September 2010
• Morphine
  ...|title=The effects of NMDA receptor antagonists and nitric oxide synthase inhibitors on opioid tolerance and withdrawal. Medication development issues for opiat ...i=10.1002/med.20035}}</ref> via [[glucuronidation]] by phase II metabolism enzyme [[UGT2B7|UDP-glucuronosyl transferase-2B7]] (UGT2B7). About 60% of morphine
  87 KB (12,376 words) - 16:51, 27 September 2010
• Diazepam
  ...as [[glucuronidation]] in the [[liver]] as part of the [[cytochrome P450]] enzyme system. Diazepam has several pharmacologically [[active metabolites]]. The Diazepam does not increase or decrease hepatic enzyme activity, and does not alter the metabolism of other compounds. There is no
  78 KB (10,295 words) - 16:51, 27 September 2010
• Digitalis lanata
  ...n is being replaced by newer drugs including angiotensin-converting enzyme inhibitors, and the calcium channel blocking agents. As new pharmacotherapeutic agents
  8 KB (1,193 words) - 12:26, 7 July 2010
• Cilazapril
  '''Cilazapril''' is a [[pyridazine]] [[angiotensin-converting enzyme]] inhibitor ([[ACE inhibitor]]) used for the treatment of [[hypertension]] {{ACE inhibitors}}
  2 KB (224 words) - 09:44, 20 September 2010
• Lisinopril
  ...'lye-SIN-o-pril'') is a drug of the [[ACE inhibitor|angiotensin converting enzyme (ACE) inhibitor]] class that is primarily used in treatment of [[hypertensi ...> Lisinopril has a number of properties that distinguish it from other ACE inhibitors: it is [[Hydrophile|hydrophilic]], has long [[half-life]] and tissue penetr
  10 KB (1,316 words) - 09:44, 20 September 2010
• Gemopatrilat
  '''Gemopatrilat''' is a drug which acts as an [[vasopeptidase]] [[enzyme inhibitor|inhibitor]].<ref name="pmid12472769">{{cite journal |author=Laver {{ACE inhibitors}}
  2 KB (256 words) - 09:44, 20 September 2010
• Renin inhibitor
  '''Renin inhibitor''', or inhibitors of [[renin]], are a new group of [[pharmaceutical]]s that are used primaril ...me="ref 1"> [http://pharmaxchange.info/presentations/dri.html Direct Renin Inhibitors Presentation]</ref>
  5 KB (697 words) - 09:44, 20 September 2010
• Thiomer
  ...xhibit mucoadhesive, permeation enhancing, controlled release as well as [[enzyme]] and [[efflux pump]] inhibitory properties. These features make the thiome ...chnürch A. In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. Biomaterials 2006;27(34):5855-60.
  4 KB (563 words) - 10:09, 20 September 2010

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