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• Sulfamethoxazole
  ...umans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over
  7 KB (978 words) - 13:12, 20 September 2010
• Crystal violet
  ...first4=L.P. | last5=Tainter | first5=M.L. | year=1972 | title= Acute oral toxicity of methylrosaniline chloride | volume=22 | pages=1–5 | doi=10.1016/0041-0 ...912.<ref>{{citation | last=Churchman | first=J.W. | year=1912 | title= The selective bactericidal action of gentian violet | journal= Journal of Experimental Me
  21 KB (3,043 words) - 13:13, 20 September 2010
• Cancer
  ...men by about 50%. A recent{{When|date=May 2010}} study reported that the [[selective estrogen receptor modulator]] [[raloxifene]] has similar benefits to [[tamo The effect of [[COX-2 selective inhibitor|COX-2 inhibitors]] such as [[rofecoxib]] and [[celecoxib]] upon t
  94 KB (13,321 words) - 21:32, 20 September 2010
• Benzene
  ...demand for other xylene isomers, a refinement of the TDP process called '''Selective TDP''' (STDP) may be used. In this process, the xylene stream exiting the T ...tly used as an industrial solvent, especially for degreasing metal. As its toxicity became obvious, benzene was supplanted by other solvents, especially [[tolu
  45 KB (6,444 words) - 21:33, 20 September 2010
• Crown ether
  ...The high affinity of 18-crown-6 for potassium ions contributes towards its toxicity. ...her Compounds and Their Application to an Ion Sensing Component for an Ion-Selective Electrode |journal = Anal. Chem. |year = 1995 |volume = 67 |pages = 324–3
  6 KB (864 words) - 20:14, 21 September 2010
• Partition coefficient
  ...tribution within the body (''e.g.'', [[intracellular]]), are somewhat less selective in their binding to proteins, and finally are often extensively metabolized ...ite journal |author= Cronin D, Mark T |title=The Role of Hydrophobicity in Toxicity Prediction|journal=Current Computer - Aided Drug Design |volume=2 |issue=4
  27 KB (3,780 words) - 20:16, 21 September 2010
• Stability constants of complexes
  ....|coauthors=Contino, A; Longo, E; Sciotto, D; Spoto, G; J.|date=2001|title=Selective complexation of soft Pb2+ and Hg2+ by a novel allyl functionalized thioamid ...tration of free Gd³⁺ is almost negligible, certainly well below toxicity threshold.<ref>{{cite book|last=Runge|first=V.M.|coauthors=Scott, S.|title=
  50 KB (7,450 words) - 20:16, 21 September 2010
• Cannabinoid
  ...ub> receptors.<ref>{{cite journal |author=Huffman JW |title=The search for selective ligands for the CB₂ receptor |journal=Curr. Pharm. Des. |volume= ...binoids produced by a plant is known as the plant's cannabinoid profile. [[Selective breeding]] has been used to control the genetics of plants and modify the c
  49 KB (6,487 words) - 22:06, 21 September 2010
• Menthol
  Menthol has [[analgesic]] properties that are mediated through a selective activation of κ-[[opioid receptors]].<ref>{{cite journal | author = Galeot ...orted nutrient or herb interactions involve menthol. (−)-Menthol has low toxicity: Oral (rat) [[Median lethal dose|LD₅₀]]: 3300&thinsp;mg/kg; Skin
  15 KB (2,008 words) - 22:07, 21 September 2010
• JWH-015
  ...-133]].<ref>Marriott KS, Huffman JW. Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor. ''Current Topics in Medicinal C ...sposition''. 2002 Oct;30(10):1077-86. PMID 12228183</ref> [[Benzo(a)pyrene#Toxicity|Epoxidation of polycyclic aromatic hydrocarbons]] can produce [[carcinogeni
  4 KB (576 words) - 22:08, 21 September 2010
• AM-694
  ...luoropentyl)-3-(2-iodobenzoyl)indole) is a drug which acts as a potent and selective [[agonist]] for the [[cannabinoid receptor]] [[Cannabinoid receptor 1|CB<su ...f these drugs, with concerns instead relating to the potential for chronic toxicity with extended use.
  4 KB (545 words) - 22:09, 21 September 2010
• Excitotoxicity
  ...apse and further rises in postsynaptic calcium levels, contributing to the selective vulnerability of MNs in ALS. Jaiswal et al., 2009.<ref name="pmid19545440"> ...izure]] activity, though this report went unnoticed for several years. The toxicity of glutamate was then observed by [[D. R. Lucas]] and [[J. P. Newhouse]] in
  11 KB (1,547 words) - 22:11, 21 September 2010
• Salvia divinorum
  ...l. 2009]].</ref> ''Salvia divinorum'' is generally understood to be of low toxicity (high [[LD50|LD₅₀]])<ref name="Mowry2003p382" /><ref>[[#refGrund ...anshahidi2006p431" /> Research has shown that salvinorin A is a potent and selective [[Kappa opioid receptor|κ-Opioid (kappa-Opioid) receptor]] [[agonist]].<re
  133 KB (18,241 words) - 22:14, 21 September 2010
• Ketorolac
  ...[[enzyme]] [[cyclooxygenase]] (COX). Like most NSAIDs, ketorolac is a non-selective COX inhibitor. ...ed]] for obstetrical administration and has demonstrable [[Fetus|fetal]] [[toxicity]] in [[Animal testing|laboratory animals]].
  16 KB (2,012 words) - 22:15, 21 September 2010
• Diclofenac
  ...ecommended to replace use of diclofenac, due to side effects in humans and toxicity in livestock eaten by vultures.<ref name=BBC3/> ...s alleging wrongful death by [[heart attack]], yet other significantly COX-selective NSAIDs such as diclofenac have been well-tolerated by most of the populatio
  28 KB (3,886 words) - 22:16, 21 September 2010
• Meloxicam
  Meloxicam use can result in gastrointestinal toxicity and bleeding, [[tinnitus]], blinding headaches, rash, very dark or black st | title = Improvement in gastrointestinal tolerability of the selective cyclooxygenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: resul
  11 KB (1,540 words) - 22:16, 21 September 2010
• Etodolac
  ...onstrated that etodolac inhibition of [[cyclooxygenase]] is somewhat COX-2 selective <ref> http://www.pnas.org/content/96/13/7563.short </ref> similar to [[cele ...ions. Patients also taking [[ciclosporin]] (Sandimmune) can develop kidney toxicity. Use in [[children]] has not been adequately studied. Etodolac is not hab
  8 KB (1,051 words) - 22:16, 21 September 2010
• COX-2 inhibitor
  '''COX-2 selective inhibitor''' is a form of [[Non-steroidal anti-inflammatory drug]] (NSAID) ...Laine L, Reicin A, ''et al.'' |title=Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Stud
  30 KB (4,194 words) - 22:17, 21 September 2010
• Piroxicam
  Piroxicam is an [[NSAID]] and, as such, is a non-selective [[cyclooxygenase|COX]] inhibitor possessing both analgesic and [[antipyreti Piroxicam use can result in [[gastrointestinal]] toxicity, [[tinnitus]], [[dizziness]], [[headache]], [[rash]], and [[pruritus]]. Th
  4 KB (444 words) - 22:17, 21 September 2010
• Non-steroidal anti-inflammatory drug
  ===Selective COX-2 inhibitors (Coxibs)=== ...y, Pm; Baigent, C; Godwin, J; Halls, H; Emberson, Jr; Patrono, C |title=Do selective cyclo-oxygenase-2 inhibitors and traditional nonsteroidal anti-inflammatory
  35 KB (4,649 words) - 22:18, 21 September 2010

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