Search results

• Mefloquine
  ...injury, it is reasonable to suppose that such events may contribute to the clinical neuropathy of the drug."<ref name="Dow2004" /> 1. "At the time this study was conceived, no formal FDA guidelines for neurotoxicity testing existed.
  13 KB (1,807 words) - 16:41, 27 September 2010
• Dexamethasone
  ...erative removal of impacted third molar teeth |journal=European Journal of Clinical Pharmacology |volume=44 |issue=3 |pages=275–277 |year=2004 |pmid= 8491244 ...ino T, Ichijo T, Chrousos GP |title=Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder
  18 KB (2,498 words) - 16:41, 27 September 2010
• Acetylcysteine
  ==Clinical use== ...d reactions to intravenous N-acetylcysteine: a prospective case controlled study |journal=Accid Emerg Nurs |volume=12 |issue=1 |pages=10–5 |year=2004 |mon
  28 KB (3,682 words) - 16:42, 27 September 2010
• Carbamazepine
  ...on of therapy.<ref>{{cite book|last=Bauer |first=Larry A. |title=[[Applied Clinical Pharmacokinetics]] |edition=2^nd |year=2008 |publisher=[[McGraw-H ...ting effect on the peripheral auditory system: auditory brainstem response study |journal=J. Child Neurol. |volume=19 |issue=6 |pages=453–5 |year=2004 |mo
  16 KB (2,164 words) - 16:42, 27 September 2010
• Phenobarbital
  | authorlink = National Institute for Health and Clinical Excellence ...leptic attacks were susceptible to the drug. Hauptmann performed a careful study of his patients over an extended period. Most of these patients were using
  20 KB (2,657 words) - 16:42, 27 September 2010
• Phenytoin
  ...emarkable Medicine Has Been Overlooked: Including an Autobiography and the Clinical Section of the Broad Range of Use of Phenytoin |publisher=Continuum Interna ...oughts compared to placebo-takers. Although phenytoin was not named in the study, the FDA announced that it expected the risk applied to every epilepsy drug
  12 KB (1,686 words) - 16:42, 27 September 2010
• Levamisole
  ==Clinical use== ...[[fluorouracil]] to treat [[colon cancer]]. There is no good evidence from clinical trials that its addition to fluorouracil therapy benefits patients with col
  10 KB (1,350 words) - 16:42, 27 September 2010
• Praziquantel
  A study found that the antibiotic [[rifampicin]] decreases plasmatic concentrations ...l.<ref>{{cite journal |author=Quinn DI, Day RO |title=Drug interactions of clinical importance. An updated guide |journal=Drug Saf |volume=12 |issue=6 |pages=3
  12 KB (1,580 words) - 16:42, 27 September 2010
• Clindamycin
  ...97)70177-4}}</ref> A [[blind experiment#Single-blind trials|single-blind]] study comparing this combination to [[adapalene]], a [[retinoid]], also found it ...ear=2003 |pmid=12963897|doi=10.1067/S0190-9622(03)01152-6}}</ref> a single study found [[wikt:pretreatment|pretreatment]] with adapalene (application of ada
  25 KB (3,261 words) - 14:17, 11 September 2010
• Chloramphenicol
  ...Wallerstein R, Condit P, Kasper C, Brown J, Morrison F | title = Statewide study of chloramphenicol therapy and fatal aplastic anemia. | journal = JAMA | vo ...k of childhood [[leukemia]] as demonstrated in a Chinese [[case-controlled study]],<ref>{{cite journal | author = Shu X, Gao Y, Linet M, Brinton L, Gao R, J
  29 KB (3,876 words) - 16:42, 27 September 2010
• Doxycycline
  ...ff A, Massung RF, Christensson B |title=Human granulocytic ehrlichiosis--a clinical case in Scandinavia |journal=Scand. J. Infect. Dis. |volume=33 |issue=1 |pa ...N, Erwin M, Sader HS |title=[Evaluation of antimicrobial sensitivity of 87 clinical isolates of vancomycin-resistant enterococci] |language=Portuguese |journal
  20 KB (2,578 words) - 16:43, 27 September 2010
• Metronidazole
  A 2005 study found "Metronidazole therapy before 32 weeks was associated with an increas ...m birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study |journal=BJOG |volume=113 |issue=1 |pages=65–74 |year=2006 |pmid=16398774
  19 KB (2,528 words) - 16:43, 27 September 2010
• Nitrofurantoin
  ...re mutually antagonistic ''in vitro''. It is not known whether this is of clinical significance, but the combination should be avoided. ...ef>{{cite journal | author=Richards WA, ''et al.'' | title=Nitrofurantoin: Clinical and laboratory studies in urinary tract infections | journal=Arch Intern Me
  12 KB (1,576 words) - 16:43, 27 September 2010
• Trimethoprim
  ...nsed to various [[generic drug|generic pharmaceutical]] manufacturers. In clinical use it is often abbreviated '''TRI''' or '''TMP'''; its common laboratory a ...ve steps in folate synthesis. This claimed benefit was not seen in general clinical use.<ref>{{cite journal |author=Brumfitt W, Hamilton-Miller JM |title=Reass
  8 KB (1,056 words) - 20:12, 10 September 2010
• Vancomycin
  ==Clinical use== |title=Serum vancomycin concentrations: reappraisal of their clinical value
  31 KB (4,198 words) - 16:43, 27 September 2010
• Clofazimine
  ...olerate the effects of [[Dapsone]] for Tuberculosis.<ref name="ReferenceA">Clinical Microbiology Made Ridiculously Simple</ref> ...researcher named Chang identified its effectiveness against leprosy. After clinical trials in Nigeria and elsewhere during the 1960s, some sponsored by the Swi
  12 KB (1,651 words) - 16:43, 27 September 2010
• Dapsone
  ...treatment of brown recluse spider envenomation: a double-blind, controlled study in a rabbit model. Arch Dermatol 2005; 141(5):595-7.</ref>; however, dapson
  15 KB (2,087 words) - 16:43, 27 September 2010
• Pyrazinamide
  ...Organisation|WHO]] recommend its use in pregnancy; and there is extensive clinical experience to show that it is safe. In the U.S., pyrazinamide is not used | title = Clinical and molecular analysis of patients with renal hypouricemia in Japan-influen
  12 KB (1,557 words) - 16:44, 27 September 2010
• Aciclovir
  ==Clinical use== HIV-1 progression can be delayed by using Aciclovir, according to study lead by Dr Jairam Lingappa. Effective in 16% of cases, can delay the HAART
  14 KB (1,878 words) - 16:44, 27 September 2010
• Lamivudine
  ...discovered accidentally when a patient took Zidovudine secretly while in a clinical trial of Lmivudine monotherapy. Dr. Yung-Chi Cheng of [[Yale University]] ...h level resistance, because the resistant virus is "less fit". The COLATE study has suggested that there is no benefit to continuing lamivudine treatment i
  9 KB (1,248 words) - 16:44, 27 September 2010
• Tenofovir
  ...s. There are no study results demonstrating the effect of tenofovir on the clinical progression of HIV. ...duced rate, the researchers cautioned against drawing conclusions from the study because the sample size was so small.<ref>
  6 KB (871 words) - 16:45, 27 September 2010
• Nevirapine
  ...|author= Patel SS, Benfield P |title=New drug profile: nevirapine |journal=Clinical Immunotherapeutics |volume=6|issue=4|pages=307–317 |year=1996 |month=Oct ...ed patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study |journal=JAMA |volume=279 |issue=12 |pages=930–7 |year=1998 |month=Mar |p
  15 KB (2,090 words) - 16:45, 27 September 2010
• Lopinavir
  ...tal reports state that lopinavir cannot be detected in the CSF; however, a study of paired CSF-plasma samples from 26 patients receiving lopinavir/ritonavir ...observed with lopinavir/ritonavir are [[diarrhea]] and [[nausea]]. In key clinical trials, moderate or severe diarrhea occurred in up to 27% of patients, and
  8 KB (1,109 words) - 16:45, 27 September 2010
• Ribavirin
  ...|last15=Schrenk |first15=UM |last16=Dieterich |first16=DT |last17=Apricot Study |first17=Group}}</ref> ...for HIV/AIDS patients. However, ribavirin has proven to have little if any clinical usefulness against HIV, and it can greatly increase blood levels and also t
  23 KB (3,222 words) - 16:45, 27 September 2010
• Codeine
  ...drug interactions of morphine, codeine, and their derivatives: theory and clinical reality, Part II |journal=Psychosomatics |volume=44 |issue=6 |pages=515–2 ...91, when the aforementioned organisation undertook its first comprehensive study of Schedule V and overall codeine, dihydrocodeine, ethylmorphine, and hydro
  40 KB (5,581 words) - 16:45, 27 September 2010
• Ketamine
  Ketamine was invented as CL369, and it was referred to as CI 581 (clinical investigation 581) during development at Parke-Davis.<ref name="Jansen23">{ ...al amitriptyline and ketamine in neuropathic pain syndromes: an open-label study |journal=The Journal of Pain |volume=6 |issue=10 |pages=644–9 |year=2005
  69 KB (9,697 words) - 21:01, 24 September 2010
• Ciprofloxacin
  ...| last1 = Kawahara | first1 = S. | title = [Chemotherapeutic agents under study] | journal = Nippon Rinsho | volume = 56 | issue = 12 | pages = 3096–9 | .... Dikov |title=A Prospective, Randomized, Double-Blind, Placebo-Controlled Study Of Antibiotics For The Treatment Of Category Iiib Chronic Pelvic Pain Syndr
  88 KB (11,930 words) - 16:46, 27 September 2010
• Sodium thiopental
  ...current Supreme Court challenges to the lethal injection protocol, after a study in the medical journal ''[[The Lancet]]'', where autopsy studies on execute ...D''] August 1997, AANA Archives-Library</ref> Dr. John S. Lundy started a clinical trial of thiopental at the [[Mayo Clinic]] at the request of Abbott.<ref>[h
  24 KB (3,339 words) - 16:46, 27 September 2010
• Tenofovir/emtricitabine
  ...tive measure if taken daily or weekly leading up to exposure, though human clinical trials are ongoing [http://www.sfgate.com/cgi-bin/article.cgi?f=/n/a/2006/0 ==Clinical Studies==
  3 KB (396 words) - 15:07, 6 July 2010
• Methylene blue
  }}</ref> especially due to its low price. Several clinical trials are in progress, trying to find a suitable drug combination. Initial | title=Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine
  27 KB (3,650 words) - 16:46, 27 September 2010
• Metformin
  ...laborating Centre for Chronic Conditions | title=Type 2 diabetes: national clinical guideline for management in primary and secondary care (update) | location= ...in people, and in 1957, French physician Jean Sterne published the first [[clinical trial]] of metformin as a treatment for diabetes. It was introduced to the
  66 KB (8,976 words) - 16:47, 27 September 2010
• Valproic acid
  '''Valproic acid''' ('''VPA''') is a [[chemical compound]] that has found clinical use as an [[anticonvulsant]] and [[mood stabilizer|mood-stabilizing]] [[med ...s and bipolar disorder.<ref>Henry T.R. (2003). The History of Valproate in Clinical Neuroscience. ''Psychopharmacology bulletin'' 37 (Suppl 2):5-16</ref>
  25 KB (3,328 words) - 16:47, 27 September 2010
• Fluoxetine
  ...treatment of major depression: results of a placebo-controlled, randomized clinical trial |journal=J Clin Psychopharmacol |volume=20 |issue=4 |pages=423–7 |y ...Kinoshita T |title=ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder |journal=
  52 KB (7,168 words) - 16:47, 27 September 2010
• Aspirin
  ...yocardial infarction (the AFTER study): a multicentre unblinded randomised clinical trial|journal = BMJ| volume = 313|issue = 7070|pages = 1429–1431|publishe ...Mortality, 1918%u20131919 Pharmacology, Pathology, and Historic Evidence. Clinical Infectious Diseases, 2009; DOI: 10.1086/606060</ref> Aspirin's profitabilit
  78 KB (10,918 words) - 16:52, 27 September 2010
• Omeprazole
  ==Clinical use== ...a]], [[dizziness]], trouble awakening and sleep deprivation, although in [[clinical trial]]s the incidence of these effects with omeprazole was mostly comparab
  17 KB (2,299 words) - 09:15, 5 September 2010
• Amlodipine
  ...lopment of [[breast]]s in [[man|men]] ([[gynecomastia]]), [[impotence]], [[Clinical depression|depression]], [[insomnia]], [[tachycardia]], [[gingival enlargem ...practice: results from the STRONG prospective, observational, multicenter study
  12 KB (1,641 words) - 15:32, 16 September 2010
• Hydralazine
  == Clinical Use == ...t al. Do selected drugs increase the risk of lupus? A matched case-control study. Br J Clin Pharmacol. 2010 Oct;70(4):588-96. doi: 10.1111/j.1365-2125.2010.
  5 KB (641 words) - 16:48, 27 September 2010
• Digoxin
  ...51/2/251}}</ref>. This negatively chronotropic effect is important for its clinical use in different arrhythmias (see below). ==Clinical use==
  19 KB (2,738 words) - 16:48, 27 September 2010
• Simvastatin
  In one non-[[Randomized controlled trials|randomized]] study, simvastatin halved the risk of developing [[dementia]] or [[Parkinson's di ...s as well, simvastatin was the first statin drug to be used extensively in clinical practice.
  14 KB (1,967 words) - 16:48, 27 September 2010
• Dopamine
  ...ire, and pleasure have come from studies performed on animals. In one such study, rats were depleted of dopamine by up to 99 percent in the [[nucleus accumb ...e rat's consummatory pleasure, only the desire to actually eat. In another study, mutant hyperdopaminergic (increased dopamine) mice show higher "wanting" b
  48 KB (6,470 words) - 16:48, 27 September 2010
• Azathioprine
  ...i-rejection regime, until [[ciclosporin|cyclosporine]] was introduced into clinical practice (also by Calne) in 1978. ...ssive regimens in renal transplantation: a systematic review and modelling study | journal=Health Technol Assess | volume=9 | issue=21 | pages=1–194 | yea
  11 KB (1,410 words) - 16:49, 27 September 2010
• Ranitidine
  ==Clinical use== ...ing drug for many years. When omeprazole and ranitidine were compared in a study of 144 people with severe inflammation and erosions or ulcers of the esopha
  5 KB (699 words) - 16:49, 27 September 2010
• Metoclopramide
  ...of study data by the FDA showed that about 20 percent of patients in that study who used metoclopramide took it for longer than three months.<ref name="Abo ==Clinical use==
  11 KB (1,453 words) - 16:49, 27 September 2010
• Cortisol
  ...l levels have been observed in connection with abnormal [[ACTH]] levels, [[clinical depression]], [[stress (psychology)|psychological stress]], and such physio ...A. (1965) “Antidiuretic Hormone in Adrenal Insufficiency”. Journal of Clinical Investigation 44: 1041,.</ref> and other different animal mechanisms operat
  41 KB (5,644 words) - 16:50, 27 September 2010
• Ibuprofen
  ...s Handbook | isbn = 0-9578521-4-2 | author = | oclc = 224121065}}</ref> A study from 2010 has shown that regular use of NSAIDs was associated with an incre ...TJ. | title=Acute poisoning due to non-steroidal anti-inflammatory drugs. Clinical features and management. | journal= Med Toxicol | year=1986 | pages=12–31
  29 KB (3,955 words) - 22:17, 21 September 2010
• Nitrous oxide
  ...being engineered and produced already in 1794, the way was now paved for [[clinical trial]]s, which began when [[Thomas Beddoes]] in 1798 established the ''"Pn ...ts of feeling "high", but did not alter psycho-motor performance, in human clinical studies.<ref name="zacny">{{cite journal|title = Flumazenil may attenuate s
  61 KB (8,728 words) - 16:50, 27 September 2010
• Mercury (element)
  ...to mercury thermometers and sphygmomanometers being largely phased out in clinical environments in favor of [[alcohol]]-filled, digital, or [[thermistor]]-bas ...alth from coal fired power plants' mercury emissions documented in the EPA Study Report to Congress of 1998.<ref name="nj vs epa">{{cite news|url=http://pac
  69 KB (10,077 words) - 21:35, 20 September 2010
• Zidovudine
  ...cers were caused by retroviruses, but this knowledge was of limited use in clinical settings due to a lack of drugs that were effective against them. The devel ...M198909143211106 | author=Yarchoan R, Mitsuya H, Myers C, Broder S | title=Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related di
  21 KB (3,049 words) - 16:51, 27 September 2010
• Morphine
  In clinical medicine, morphine is regarded as the gold standard, or benchmark, of analg ...=http://books.google.com/?id=MtOiLVWBn8cC&pg=PA20|page=20|title=Molecular, clinical and environmental toxicology|author=Andreas Luch|publisher=Springer|year=20
  87 KB (12,376 words) - 16:51, 27 September 2010
• Paracetamol
  ...and New Zealand—explanation and elaboration. A consensus statement from clinical toxicologists consulting to the Australasian poisons information centres |j ...name=pmid17227290/> In 1893, von Mering published a paper reporting on the clinical results of paracetamol with [[phenacetin]], another aniline derivative.<ref
  54 KB (7,376 words) - 16:52, 27 September 2010

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