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• Dexamethasone
  ...eroid]] drugs. It acts as an [[anti-inflammatory]] and [[immunosuppressive drug|immunosuppressant]]. It is 20 to 30 times more potent than the naturally oc ...g [[chemotherapy]] are given Dexamethasone to counteract certain [[Adverse drug reaction|side-effects]] of their antitumor treatment. Dexamethasone can aug
  18 KB (2,498 words) - 16:41, 27 September 2010
• Acetylcysteine
  ...Australia|Aus]])<br />[[Over-the-counter substance|OTC]] or [[Prescription drug|Rx]] ([[U.S.]]) ...''-acetyl-''L''-cysteine''' (abbreviated '''NAC'''), is a [[pharmaceutical drug]] and [[nutritional supplement]] used primarily as a [[mucolytic agent]] an
  28 KB (3,682 words) - 16:42, 27 September 2010
• Naloxone
  ...ass_name=%2804%2E2%2E%29Specific%20antidotes%3Cbr%3E|website=International Drug Price Indicator Guide|accessdate=13 August 2015}}</ref> ...mergency overdose response kits distributed to [[heroin]] and other opioid drug users and emergency responders. This has been shown to reduce rates of dea
  33 KB (4,541 words) - 10:57, 17 June 2016
• Phenobarbital
  ...synthesized by Fischer. Phenobarbital was brought to market in 1912 by the drug company Bayer using the brand Luminal. It remained a commonly prescribed se | title = Drug Discovery
  20 KB (2,657 words) - 16:42, 27 September 2010
• Codeine
  ...ies and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17 |journal=Drug Metab. Dispos. |volume=35 |issue=8 |pages=1292–300 |year=2007 |month=Augu ...most widely used opiate in the world, and probably the most commonly used drug overall according to numerous reports by organizations including the World
  40 KB (5,581 words) - 16:45, 27 September 2010
• Ketamine
  ...isoforms to N-demethylation of ketamine in human liver microsomes |journal=Drug Metabolism and Disposition |volume=30 |issue=7 |pages=853–8 |year=2002 |m ...r=1999 |pmid=10551055 |pmc=2148883}}</ref> and is used as a [[recreational drug]].
  69 KB (9,697 words) - 21:01, 24 September 2010
• List of World Health Organization Essential Medicines
  ===Medicines used in substance dependence programs=== [[Category:Drug-related lists]]
  16 KB (1,353 words) - 21:21, 3 October 2011
• Prussian blue
  ...owing to the presence of variable amounts of other ions and the sensitive dependence of its appearance to the size of the particles. The pigment is used in [[pa ...n blue capsules, when manufactured under the conditions of an approved New Drug Application (NDA), can be found safe and effective therapy" in certain pois
  20 KB (3,004 words) - 16:47, 27 September 2010
• Dopamine
  ...use dopamine cannot cross the [[blood-brain barrier]], dopamine given as a drug does not directly affect the [[central nervous system]]. To increase the am ...addiction]] (not to be confused with [[Substance dependence|psychological dependence]]), arguing that this [[dopaminergic pathways|dopamine pathway]] is patholo
  48 KB (6,470 words) - 16:48, 27 September 2010
• Nitrous oxide
  ...ic]] effects of inhaling it, a property that has led to its [[recreational drug use|recreational use]] as a [[dissociative]] [[anesthetic]]. It is also use ...ung diseases could be treated by inhalation of "Factitious Airs"<ref name="Drug discovery"/> (the word [[factitious]] means "artificial").
  61 KB (8,728 words) - 16:50, 27 September 2010
• Morphine
  {{About|the drug|other meanings|Morphine (disambiguation)}} '''[[Recreational drug use|Recreational]] uses:'''<br>
  87 KB (12,376 words) - 16:51, 27 September 2010
• Ephedrine
  ...e book | editor= Edited by Reynolds JEF | title=[[Martindale: The complete drug reference]] | edition=29th | date=1989 | publisher=Pharmaceutical Press | l [[Adverse drug reaction]]s (ADRs) are more common with systemic administration (e.g. injec
  21 KB (2,906 words) - 16:51, 27 September 2010
• Diazepam
  ...sion.<ref name="Riss-2008"/> Diazepam has also been used as a recreational drug. ...]] such as diazepam include [[drug tolerance|tolerance]], [[benzodiazepine dependence]] as well as a [[benzodiazepine withdrawal syndrome]] upon dose reduction;
  78 KB (10,295 words) - 16:51, 27 September 2010
• Digitalis
  The term '''digitalis''' is also used for [[drug]] preparations that contain [[cardiac glycoside]]s, particularly one called ...ia]]s and to slow the ventricular rate during [[atrial fibrillation]]. The dependence on the vagal effect means that digitalis is not effective when a patient ha
  15 KB (2,220 words) - 12:27, 7 July 2010
• Temazepam
  ...due to concerns of [[drug tolerance|tolerance]] and [[physical dependence|dependence]].<ref name="tembnf">{{cite web |url= http://bnf.org/bnf/bnf/55/3152.htm|ti * [[Hypersensitivity]] or allergy to any drug in the [[benzodiazepine]] class
  45 KB (6,129 words) - 22:16, 19 September 2010
• Potassium channel blocker
  ...converting someone into normal sinus rhythm. ''Because of the reverse use-dependence of class III agents, at low heart rates class III antiarrhythmic agents may ...f the action potential is uniform over a wide range of heart rates so this drug does '''not''' have reverse use-dependent action. [[Amiodarone]] was the f
  5 KB (725 words) - 09:45, 20 September 2010
• TDIQ
  ...discovery, pharmacological effects, and therapeutic potential |journal=CNS Drug Reviews |volume=13 |issue=4 |pages=405–22 |year=2007 |pmid=18078426 |doi=
  4 KB (449 words) - 13:15, 20 September 2010
• Partition coefficient
  A drug's distribution coefficient strongly affects how easily the drug can reach its intended target in the body, how strong an effect it will hav ...gain.<ref name="Kubinyi">{{cite journal |author=Kubinyi H |title=Nonlinear dependence of biological activity on hydrophobic character: the bilinear model|journal
  27 KB (3,780 words) - 20:16, 21 September 2010
• Stability constants of complexes
  === Ionic strength dependence === [[image:Cu gly ionic strength.png|thumb|Dependence of the stability constant for formation of [Cu(glycinate)]⁺ on i
  50 KB (7,450 words) - 20:16, 21 September 2010
• Solubility equilibrium
  ...ly weak and usually neglected in practice. Assuming an ideal solution, the dependence can be quantified as: The pressure dependence of solubility does occasionally have practical significance. For example, [
  23 KB (3,592 words) - 20:16, 21 September 2010
• Acid dissociation constant
  ===Temperature dependence=== ...olubility in water, but decrease the lipophilicity. This is exploited in [[drug development]] to increase the concentration of a compound in the blood by a
  76 KB (11,861 words) - 20:17, 21 September 2010
• Equilibrium chemistry
  ...ite book|last=Blandamer|first=M.J.|title=Chemical equilibria in solution : dependence of rate and equilibrium constants on temperature and pressure|publisher=Ell ...m/wps/find/journaldescription.cws_home/30921/description#description|title=Drug discovery today|accessdate=23 March 2010}}</ref>
  42 KB (6,675 words) - 20:17, 21 September 2010
• Chemical equilibrium
  ...ant for pharmaceuticals where lipophilicity is a significant property of a drug *Prediction of temperature dependence of lg K values using various thermodynamic models
  38 KB (5,847 words) - 20:17, 21 September 2010
• Ziconotide
  In December 2004 the [[Food and Drug Administration]] approved ziconotide [[route of administration|when deliver ...ation. It was approved for sale under the name Prialt by the U.S. Food and Drug Administration on December 28, 2004, and by the [[European Commission]] on
  8 KB (1,082 words) - 22:04, 21 September 2010
• Amobarbital
  ...xtended periods of time, physical and [[Substance dependence|psychological dependence]] can develop. ...nd to death but claimed innocence. He was surreptitiously administered the drug, by his [[Lawyer|attorney]], and under the influence of it he revealed why
  9 KB (1,128 words) - 22:04, 21 September 2010
• Tectin (drug)
  '''Tectin''' is the brand name of a [[pain killing drug]] currently in development by [[WEX Pharmaceuticals Inc.]] The drug comes from a toxin in the [[pufferfish]] called [[tetrodotoxin]], a very po
  2 KB (272 words) - 22:05, 21 September 2010
• Fioricet
  Side effects for any drug are difficult to predict, but commonly reported side effects for Fioricet i *[[Substance dependence]]
  3 KB (378 words) - 22:06, 21 September 2010
• JWH-015
  ...pon CB₁ and CB₂ receptor binding. ''Drug and Alcohol Dependence'' 2000; 60:133-140.</ref> However it still displays some weak CB<sub>1</sub ...yl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist. ''Drug Metabolism and Disposition''. 2002 Oct;30(10):1077-86. PMID 12228183</ref>
  4 KB (576 words) - 22:08, 21 September 2010
• Tetrahydrocannabinol
  ...ng a [[dopamine]] release in the [[nucleus accumbens]]. The effects of the drug can be suppressed by the CB1 [[cannabinoid receptor]] antagonist [[rimonaba | journal = Current Drug Targets-Cns and Neurological Disorders-
  50 KB (6,686 words) - 22:09, 21 September 2010
• JWH-019
  ...ic indoles upon CB(1) and CB(2) receptor binding |journal=Drug and Alcohol Dependence |volume=60 |issue=2 |pages=133–40 |year=2000 |month=August |pmid=10940540
  3 KB (440 words) - 22:10, 21 September 2010
• Cannabis smoking
  ...by heating the flowers and subtending leaves and stems of the [[Cannabis (drug)|Cannabis sativa]] and Indica plants, known as [[marijuana]]. Alternatively ...url=http://www.unodc.org/pdf/WDR_2006/wdr2006_chap2_annex1.pdf|title=World Drug Report|volume=1|id=ISBN 92-1-148214-3|accessdate=2007-11-22|pages=187–192
  12 KB (1,680 words) - 22:10, 21 September 2010
• Cannabis
  {{About|the plant genus|use as a psychoactive drug in the genus|Cannabis (drug)}} ...ychoactive]] molecule that produces the "high" associated with [[cannabis (drug)|marijuana]]. The psychoactive product consists of dried flowers and leaves
  76 KB (10,798 words) - 22:10, 21 September 2010
• Marijuana Anonymous
  ...am]] for people with common desire to maintain abstinence from [[Cannabis (drug)|marijuana]].<ref name="washtimes">{{cite news|url=|title= Addicted to weed ...>{{cite book|title=A brief cognitive-behavioural intervention for cannabis dependence: Therapists' treatment manual|author=Vaughan Rees, Jan Copeland and Wendy S
  2 KB (298 words) - 22:10, 21 September 2010
• Marijuana and the brain
  ...minating the complexities involved in rehabilitation and in treatments for drug addiction. Despite cognitive, social as well as neurological evidence to t ...affective response in marijuana smokers: an fmri study. ''Drug and Alcohol Dependence, 105,'' 139-153.</ref> have been shown in marijuana users. This suggests t
  46 KB (6,708 words) - 22:10, 21 September 2010
• Cannabis withdrawal
  At one time cannabis was considered a drug that had no withdrawal symptoms because users did not display symptoms simi ...laboratory research has focused on the role of brain chemistry in cannabis dependence. As with other drugs, cannabis increases the production of [[dopamine]], a
  4 KB (577 words) - 22:11, 21 September 2010
• Smoking cessation (cannabis)
  ...nt services in Australia 2003-04: Report on the national minimum data set. Drug Treatment Series 4. AIHW cat. no. HSE 100 Canberra, Australian Institute of ==Cannabis dependence==
  20 KB (2,835 words) - 22:11, 21 September 2010
• Cannabis (drug)
  ...from the hemp plant Cannabis sativa...is the most commonly abused illicit drug in the United States"[http://www.drugabuse.gov/Infofacts/marijuana.html] -- ...ailable in the United Kingdom (UK) | author = Matthew J. Atha (Independent Drug Monitoring Unit)}}</ref>
  72 KB (10,341 words) - 22:11, 21 September 2010
• Post–acute withdrawal syndrome
  ...-Hebert C, Simonpoli AM | year =1997 | month=March | title =[Management of drug addict pregnant women and their children] | journal =Arch Pediatr | volume ...ase anxiety and depression levels in some individuals. In most cases these drug induced psychiatric disorders fade away with prolonged abstinence.<ref>{{ci
  17 KB (2,125 words) - 22:12, 21 September 2010
• HCN channel
  ...the native If/Ih current, but with quantitative differences in the voltage-dependence, activation/deactivation kinetics and sensibility to cAMP: HCN1 channels sh ...themselves. By directly inhibiting HCN channels in vitro, either with the drug ZD7288 or viral knockdown of [[HCN1]] expression, the Arnsten lab was able
  8 KB (1,157 words) - 22:12, 21 September 2010
• Loperamide
  ...ational Cancer Institute, Drug Dictionary]</ref> is an opioid [[medication|drug]] effective against [[diarrhea]] resulting from [[gastroenteritis]] or [[in ...ournal|author=Nakamura H, Ishii K, Yokoyama Y, ''et al.'' |title=[Physical dependence on loperamide hydrochloride in mice and rats] |language=Japanese |journal=Y
  7 KB (989 words) - 22:12, 21 September 2010
• Buprenorphine
  ...sation. In the USA, it has been a [[Controlled Substances Act|Schedule III drug]] under the [[United Nations]]' [[Convention on Psychotropic Substances]] s ...ent [[formulation]]s{{dn}} from [[Reckitt Benckiser]] have been [[approved drug|approved]] for [[opioid]] addiction treatment throughout most of the world,
  59 KB (8,561 words) - 22:13, 21 September 2010
• Hydromorphone
  ..., according to the current version of ''The A-Z Encyclopaedia of Alcohol & Drug Abuse'' and other references. ...lity and speed of onset, a less troublesome side effect profile, and lower dependence liability as compared to [[morphine]] and [[diamorphine]] (heroin). It is t
  38 KB (5,300 words) - 22:13, 21 September 2010
• Pholcodine
  '''Pholcodine''' is a [[drug]] which is an [[opioid]] [[cough suppressant]] (antitussive). It helps supp ...usly more common [[codeine]] linctus, as it has a much lower potential for dependence.
  4 KB (591 words) - 22:13, 21 September 2010
• Methadone
  ...], used medically as an [[analgesic]], [[antitussive]] and a maintenance [[drug addiction#Anti-addictive drugs|anti-addictive]] for use in patients on opio Methadone is useful in the treatment of opioid dependence. It has [[cross-tolerance]] with other opioids including [[heroin]] and [[m
  61 KB (8,865 words) - 22:13, 21 September 2010
• Salvia divinorum
  ...a [[Psychoactive drug|psychoactive]] plant which can induce [[dissociative drug|dissociative]] effects. Its native habitat is within [[cloud forest]] in th ...ve called for its prohibition. While not currently regulated by US federal drug laws, several states have passed laws criminalizing the substance.<ref name
  133 KB (18,241 words) - 22:14, 21 September 2010
• Hydrocodone
  | '''[[Recreational drug use|Non-medical]] use/abuse:''' | '''[[Adverse drug reaction|Side effects]]:'''
  30 KB (4,151 words) - 22:14, 21 September 2010
• Dextromethorphan
  ...p]], [[Vicks]], [[Coricidin]], [[Delsym]], and others, including [[generic drug|generic]] labels. Dextromethorphan has also found other uses in medicine, r ...ug Administration]] (FDA) approved dextromethorphan for [[Over-the-counter drug|over-the-counter]] sale as a cough suppressant in 1958. This filled the nee
  26 KB (3,444 words) - 22:15, 21 September 2010
• Secobarbital
  ...below, under the brand name '''Seconal''') is a [[barbiturate]] derivative drug that was first synthesized in 1928. It possesses [[anaesthetic]], [[anticon Secobarbital is a fairly [[Substance dependence|addictive]] drug, and [[withdrawal]] symptoms can occur if long-term usage is abruptly ended
  9 KB (1,251 words) - 21:02, 24 September 2010
• Propofol
  | legal_status = [[Prescription drug|℞-only]] <small>(U.S.)</small> ...e]]. Propofol is approved for use in more than 50 countries, and [[generic drug|generic]] versions are available.
  21 KB (2,875 words) - 21:03, 24 September 2010
• Gamma-Hydroxybutyric acid
  ...n patients with [[narcolepsy]]. The same company is also investigating the drug for use as a [[fibromyalgia]] treatment.<ref>http://online.wsj.com/article/ ...y related to the [[ketone body]] [[beta-hydroxybutyrate]]. As a supplement/drug, it is used most commonly in the form of a salt.<ref>e.g., '''sodium gamma-
  55 KB (7,839 words) - 21:04, 24 September 2010

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