Diaminopyrimidine
From Self-sufficiency
Diaminopyrimidines are a class of organic chemical compounds that include two amine groups on a pyrimidine ring.
They include many dihydrofolate reductase inhibitor drugs (such as pyrimethamine, trimetrexate, and piritrexim [1] and the antibiotics Iclaprim and trimethoprim).
Some have been patented as anti-cancer drugs.[2]
See also
References
Cite error: Invalid <references>
tag;
parameter "group" is allowed only.
<references />
, or <references group="..." />
30px | This article about an organic compound is a stub. You can help ssf by expanding it. |
- ↑ http://aac.asm.org/cgi/content/full/45/12/3293 "Dicyclic and Tricyclic Diaminopyrimidine Derivatives as Potent Inhibitors of Cryptosporidium parvum Dihydrofolate Reductase: Structure-Activity and Structure-Selectivity Correlations" Nelson et al. 2001
- ↑ http://www.wipo.int/pctdb/en/wo.jsp?IA=GB1998000111&DISPLAY=DESC