Ipriflavone

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Ipriflavone
File:Ipriflavone.png
Systematic (IUPAC) name
7-isopropoxy-3-phenyl-4H-chromen-4-one
Identifiers
CAS Number 35212-22-7
ATC code M05BX01 (WHO)
PubChem CID 3747
Synonyms 3-phenyl-7-propan-2-yloxychromen-4-one
Chemical data
Formula C18H16O3
Molar mass 280.318 g/mol[[Script error: No such module "String".]]
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Ipriflavone is a synthetic isoflavone which may be used to inhibit bone resorption,[1] maintain bone density and to prevent osteoporosis in postmenopausal women. It is not used to treat osteoporosis. It slows down the action of the osteoclasts (bone-eroding cells), possibly allowing the osteoblasts (bone-building cells) to build up bone mass.

A clinical trial reported in 2001 that it was not effective in prevention or treatment of osteoporosis.[2]

References

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External links

Drugs for treatment of bone diseases (M05)
Bisphosphonates
Bone morphogenetic proteins
Other
Resorption inhibitor (Ipriflavone) · Aluminium chlorohydrate · Dual action bone agent (Strontium ranelate) ·
RANKL inhibitor (Denosumab) · Cathepsin K inhibitor (Odanacatib)
Isoflavones and their glycosides
Isoflavones
O-methylated isoflavones
Glycosides
Prenylated isoflavones
Pyranoisoflavones
Synthetic
Ipriflavone


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  1. ↑ Civitelli R (1997). "In vitro and in vivo effects of ipriflavone on bone formation and bone biomechanics". Calcified tissue international. 61 Suppl 1: S12–4. PMID 9263610. 
  2. ↑ "Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial". 2001. 
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