Naftidrofuryl

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Naftidrofuryl
File:Naftidrofuryl.svg
Systematic (IUPAC) name
2-(diethylamino)ethyl 3-(1-naphthyl)-2-(tetrahydrofuran-2-ylmethyl)propanoate
Clinical data
Routes of
administration		 Oral
Identifiers
CAS Number 31329-57-4
ATC code C04AX21 (WHO)
PubChem CID 4417
Chemical data
Formula C24H33NO3
Molar mass 383.524 g/mol[[Script error: No such module "String".]]
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Naftidrofuryl (INN, also known as nafronyl or as the oxalate salt naftidrofuryl oxalate or nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic.[1] It may also be a 5-HT2 receptor antagonist.

It is sold under the brand name Dusodril (Merck) and cerebromap for multiapex in middle east.

Historically, it has been used to treat sudden idiopathic hearing loss and acute tinnitus.[2]

References

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Peripheral vasodilators (C04)
2-amino-1-phenylethanol derivatives
Imidazoline derivatives/
Alpha blockers
Niacin and derivatives
Purine derivatives
Ergot alkaloids
Other peripheral vasodilators


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  1. ↑ Reynolds, J.E.F. (ed.) (1993). Martindale: The extra pharmacopoeia (30th edition ed.). London: Pharmaceutical Press. p. 1310. ISBN 0853693005. 
  2. ↑ http://www.der-arzneimittelbrief.de/Jahrgang2004/Ausgabe12Seite89.htm
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