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...s '''[[Symbyax]]''') is an [[antidepressant]] of the [[selective serotonin reuptake inhibitor]] (SSRI) class. It is manufactured and marketed by [[Eli Lilly an ...compounds in mice resulted in [[nisoxetine]], a selective [[norepinephrine reuptake inhibitor]] currently widely used in biochemical experiments.<ref name="dwo

|ImageFile2=Dopamine-3d-CPK.png ...cyclopedia.com/doc/1O87-ventraltegmentalarea.html Reference for VTA.</ref> Dopamine is also a [[neurohormone]] released by the [[hypothalamus]]. Its main funct

...epinephrine reuptake inhibitor|SNRI]]s (serotonin-norepinephrine re-uptake inhibitors), as this increases the risk of the above symptoms due to excessive serum l ...mode of therapeutic action involves norepinephrine and to a lesser degree dopamine, but it also releases some serotonin from presynaptic clefts. It should not

===COX-2 inhibitors=== ...analgesic effects being mediated by the COX2 (inducible) enzyme. The COX2 inhibitors were thus developed to inhibit only the COX2 enzyme (traditional NSAIDs blo

...html NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and serotonin 5-HT2receptorsimplications for models of schizophrenia](20 ...| pmid = 19391150 | doi = 10.1002/syn.20647}}</ref> as well as [[dopamine reuptake inhibitor]]s.{{Citation needed|date=April 2010}}

...16051647">{{cite journal | author = Gillman PK | title = Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity | journal = British Journal of An A large number of medications are potent inhibitors of [[CYP2D6]]. Some types of medications known to inhibit CYP2D6 include ce