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...shizawa K, Aoki K, Takagi M, Miyatake M, Suzuki T |title=A putative sigma1 receptor antagonist NE-100 attenuates the discriminative stimulus effects of ketamin ...e the effect to ketamine being an [[N-methyl-D-aspartate receptor|NMDA]] [[receptor antagonist]].<ref>{{Cite journal|author=Zarate CA, Singh JB, Carlson PJ, ''

...HT in rat prefrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study |journal=Neuropsychopharmacology |volume=27 |issue=6 |pages=9 ..., Casis O, Casis L |title=Effects of fluoxetine administration on mu-opoid receptor immunostaining in the rat forebrain |journal=Brain Res. |volume=817 |issue=

...enegger M |title=Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676 |journal=Br. J. Pharmacol. |volume=146 |issue

...D₃]], [[Dopamine D4 receptor|D₄]], and [[Dopamine D5 receptor|D₅]]—and their variants. Dopamine is produced in several areas Via the [[dopamine receptor]]s, D_1-5, dopamine reduces the influence of the indirect pathway

...that apparently only reacted to morphine: the mu3 [[Opioid receptor|opiate receptor]] in human tissue.<ref>{{cite journal |author=Zhu W, Cadet P, Baggerman G, ...de release in the mammalian gastrointestinal tract via the micro(3) opiate receptor subtype: a hormonal role for endogenous morphine|journal=Journal of Physiol

...biochemistry]] host-guest complexes are known as [[receptor (biochemistry)|receptor]]-ligand complexes; they are formed primarily by [[non-covalent bond]]ing. ...ther blocks a receptor, an [[antagonist]] which forms a strong complex the receptor, or activate it, an [[agonist]], is an important pathway to [[drug discover

* [[Mutations in estradiol receptor]]

...ot only delivering "opiate-like" effects (through mild agonism of the [[mu receptor]]) but also by acting as a weak but fast-acting [[serotonin]] and [[norepin Other psychotropic analgesic agents include [[ketamine]] (an NMDA receptor antagonist), [[clonidine]] and other α₂-adrenoreceptor agonists

...is quite different, acting primarily as [[Mu opioid receptor|mu]]-[[opioid receptor]] agonists. Other active chemicals in kratom include [[raubasine]] (best k ...The subjective effects of kratom use are similar to the effects of opiate receptor agonists such as [[codeine]] or [[hydrocodone]], and will prevent withdrawa

Loperamide is an [[opioid]]-receptor [[agonist]] and acts on the [[Mu Opioid receptor|μ-opioid receptors]] in the [[myenteric plexus]] of the large intestine; b

...antagonist|antagonist]] activity at the [[kappa opioid receptor|κ-opioid receptor]]. Buprenorphine [[hydrochloride]] was first marketed in the 1980s by Recki Suboxone contains buprenorphine as well as the [[opioid]] [[receptor antagonist|antagonist]] [[naloxone]] to deter the abuse of tablets by [[int

...hydromorphone, related to the morphine molecule, is a primary [[mu opioid receptor|μ]] agonist]. Although this can lead to addiction and reward-seeking behav Hydromorphone, a semi-synthetic [[Opioid receptor#The μ-opioid receptor|μ-opioid]] [[agonist]], is a [[hydrogenation|hydrogenated]] [[ketone]] of

...8}}</ref> In addition, it is a synthetic strong agonist at the [[mu opioid receptor|μ-opioid]] receptors. Historically it has been used to treat [[breakthroug

...2receptorsimplications for models of schizophrenia](2002)</ref> Other NMDA receptor antagonists include [[ketamine]], [[tiletamine]], and [[dextromethorphan]]. In a similar manner, PCP and analogues also inhibit [[nicotinic acetylcholine receptor]] channels (nAChR). Some analogues have greater potency at nAChR than at NM

...ssociative]] [[hallucinogen]]. Its [[mechanism of action]] is as an [[NMDA receptor antagonist]], producing effects similar to those of the controlled substan ...o JF, Chang WY, Lin MF, Chen CF | title = Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextrom

...is consumed. This metabolite is considerably more potent as a [[Mu opioid receptor|μ opioid]] [[agonist]] than the parent compound,<ref>{{cite pmid|9190321}}