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...opiates — the codeine-based antitussives in particular — in late 1973, researchers were tasked with finding a way to synthesize codeine and its derivatives. T ...orst-Paulus M|date=1986|title=Treatment of narcolepsy with codeine|journal=Sleep|volume=9|pages=269–74|pmid=3518019|first1=JM|last2=Pressman|first2=MR|las

The researchers apparently attribute the effect to ketamine being an [[N-methyl-D-aspartate ...uced ''in vivo'', would likely induce cortical oscillations reminiscent of sleep.<ref>{{Cite journal|author=Carr DB, Andrews GD, Glen WB, Lavin A |title=alp

A controversy ensued after Lilly researchers published a paper titled "Prozac (fluoxetine, Lilly 110140), the first sele ...ble-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxetine was better than placebo for the prevention of depression recurr

...volved in [[lactation]] and [[prolactin#Effects|sexual gratification]]), [[sleep]], [[Mood (psychology)|mood]], [[attention]], [[working memory]], and [[lea Dopamine's role in experiencing pleasure has been questioned by several researchers. It has been argued that dopamine is more associated with anticipatory desi

...e lowest levels present around 12-4am, or 3–5 hours after the onset of [[sleep]]. Information about the [[Circadian rhythm|light/dark cycle]] is transmitt ...of [[ACTH]] (Adrenocorticotropic hormone or corticotropin) secretion. Some researchers believe that this normal feedback system may become dysregulated when anima

....<ref name="martin and fraser" /> Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and ...Yawning, perspiration, lacrimation, crying, running nose, dysphoria, "yen sleep"

...dical)|fatigue]] and [[cachexia]] ([[wasting]]), excessive [[sweating]] ([[sleep hyperhidrosis|night sweats]]), [[anemia]] and specific [[paraneoplastic phe In addition to viruses, researchers have noted a connection between [[cancer bacteria|bacteria and certain canc

Physiological reactions to stress can have consequences for health over time. Researchers have been studying how stress affects the cardiovascular system, as well as ...re facing in the 21st century have been linked to increased stress levels. Researchers and social commentators have pointed out that the computer and communicatio

...ot appear to cause nausea or vomiting. Heavy use can result in a prolonged sleep. ...needed. Chulalongkorn University chemists have isolated mitragynine which researchers can obtain for study.

| title = Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults In November 2007, researchers at the [[California Pacific Medical Center]] reported that CBD shows promis

...89|pages=25–26|year=1997| doi=10.1038/37891|title=Anandamide may mediate sleep induction|author=Raphael Mechoulam, Ester Fride, Lumir Hanu, Tzviel Sheskin The [[mechanism of action]] of oleamide's sleep inducing effects is an area of current research. It is likely that oleamid

...nicotine, quitting cannabis caused symptoms such as irritability, anxiety, sleep problems and difficulty sleeping. Copeland et al<ref>Copeland, J., Frewen, According to a number of researchers there are several drugs that may either ease the symptoms of cannabis withd

...ntle persuasion, and reasoning with her. If this is not helpful, he should sleep apart from her, trying to awaken her agreeable feminine nature so that sere Terrorism researchers said "the memos and audiotapes, many translated from Arabic and containing