Technetium (99mTc) nofetumomab merpentan
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| File:Technetium-99m nofetumomab merpentan skeletal.svg | |
| Monoclonal antibody | |
|---|---|
| Type | Fab fragment |
| Source | Template:Infobox drug/mab source |
| Pharmacokinetic data | |
| Biological half-life | 10.5 hours |
| Excretion | renal (64%) |
| Identifiers | |
| CAS Number | 165942-79-0 |
| ATC code | none |
Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody used in the diagnosis of lung cancer[1], gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma[2]. The antibody itself, nofetumomab, is attached to the chelator merpentan, which links it to the radioisotope technetium-99m (99mTc).[3]
References
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- ↑ Straka, MR; Joyce, JM; Myers, DT (2000). "Tc-99m nofetumomab merpentan complements an equivocal bone scan for detecting skeletal metastatic disease from lung cancer". Clinical nuclear medicine. 25 (1): 54–5. PMID 10634533.
- ↑ Breitz, HB; Tyler, A; Bjorn, MJ; Lesley, T; Weiden, PL (1997). "Clinical experience with Tc-99m nofetumomab merpentan (Verluma) radioimmunoscintigraphy". Clinical nuclear medicine. 22 (9): 615–20. PMID 9298295.
- ↑ WHO Drug Information
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