Difference between revisions of "Tioclomarol"

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Latest revision as of 10:21, 20 September 2010

Tioclomarol
Systematic (IUPAC) name
File:Tioclomarol.svg
3-[3-(4-chlorophenyl)-1-(5-chloro-2-thienyl)-3-hydroxypropyl]-2-hydroxy-4H-chromen-4-one
Identifiers
ATC code	B01AA11 (WHO)
PubChem	CID 72147
Chemical data
Formula	C₂₂H₁₆Cl₂O₄S
Molar mass	447.331 g/mol[[Script error: No such module "String".]]

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Tioclomarol is a vitamin K antagonist.

Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs

Glycoprotein IIb/IIIa inhibitors	Abciximab • Eptifibatide • Tirofiban
ADP receptor/P2Y₁₂ inhibitors	thienopyridines (Clopidogrel, Prasugrel, Ticlopidine) • Ticagrelor^†
Prostaglandin analogue (PGI2)	Beraprost • Prostacyclin • Iloprost • Treprostinil
COX inhibitors	Acetylsalicylic acid/Aspirin^# • Aloxiprin • Carbasalate calcium • Indobufen • Triflusal
Thromboxane inhibitors	thromboxane synthase inhibitors (Dipyridamole, Picotamide) • receptor antagonist (Terutroban^†)
Phosphodiesterase inhibitors	Cilostazol • Dipyridamole • Triflusal
Other	Cloricromen • Ditazole

Vitamin K antagonists
(inhibit II, VII, IX, X)

coumarins: Acenocoumarol • Coumatetralyl • Dicoumarol • Ethyl biscoumacetate • Phenprocoumon • Warfarin

1,3-Indandiones: Clorindione • Diphenadione • Phenindione

other: Tioclomarol

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	low molecular weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) oligosaccharides (Fondaparinux, Idraparinux) heparinoid (Danaparoid, Sulodexide, Dermatan sulfate)
Direct Xa inhibitors	xabans (Apixaban, Betrixaban, Edoxaban, Otamixaban, Rivaroxaban)

Direct thrombin (II) inhibitors

bivalent: Hirudin (Bivalirudin, Lepirudin, Desirudin)
univalent: Argatroban • Dabigatran • Melagatran^‡ • Ximelagatran^‡

Other

REG1 • Defibrotide • Ramatroban • Antithrombin III • Protein C (Drotrecogin alfa)

Thrombolytic drugs/
fibrinolytics

plasminogen activators: r-tPA (Alteplase, Reteplase, Tenecteplase) • UPA (Urokinase, Saruplase) • Streptokinase^# • Anistreplase • Monteplase

other serine endopeptidases: Ancrod • Fibrinolysin

Citrate • EDTA • Oxalate

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

cell/phys (coag, heme, gran)

rbmg/mogr/tumr, sysi/epon, btst

drug (B1/2/3+5+6), btst

40px	This drug article relating to the blood and blood forming organs is a stub. You can help ssf by expanding it. v d e

it:Tioclomarolo

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