Odanacatib

Odanacatib
	File:Odanacatib.png
Systematic (IUPAC) name
	N-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucinamide
Clinical data
Routes of; administration	oral
Identifiers
CAS Number	603139-19-1
ATC code	none
PubChem	CID 10152654
Synonyms	(2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-(methanesulfonyl)-[1,1'-biphenyl]-4-yl}ethyl]amino}pentanamide
Chemical data
Formula	C25H27F4N3O3S
Molar mass	525.56 g/mol[[Script error: No such module "String".]]
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Odanacatib (pINN; codenamed MK-0822) is an investigational treatment for osteoporosis and bone metastasis^[1]. It is an inhibitor of cathepsin K,^[2] an enzyme involved in bone resorption.

It is being developed by Merck & Co. As of November 2009^[update], Merck is conducting phase III clinical trials.

References

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↑ Le Gall, C. L.; Bonnelye, E.; Clézardin, P. (2008). "Cathepsin K inhibitors as treatment of bone metastasis". Current Opinion in Supportive and Palliative Care. 2 (3): 218. doi:10.1097/SPC.0b013e32830baea9. PMID 18685424. edit
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Systematic (IUPAC) name
File:Odanacatib.png
N-(1-cyanocyclopropyl)-4-fluoro-N²-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucinamide
Clinical data
Routes of administration	oral
Identifiers
CAS Number	603139-19-1
ATC code	none
PubChem	CID 10152654
Synonyms	(2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-(methanesulfonyl)-[1,1'-biphenyl]-4-yl}ethyl]amino}pentanamide
Chemical data
Formula	C₂₅H₂₇F₄N₃O₃S
Molar mass	525.56 g/mol[[Script error: No such module "String".]]
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