Mequinol

Mequinol

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Systematic (IUPAC) name
4-Methoxyphenol
Clinical data
Routes of administration	Topical
Legal status
Legal status	CA: Unscheduled US: Rx-only, Unscheduled Unscheduled
Identifiers
CAS Number	150-76-5
ATC code	D11AX06 (WHO)
PubChem	CID 9015
Synonyms	4-Hydroxyanisole; para-Guaiacol
Chemical data
Formula	C7H8O2
Molar mass	124.13722 g/mol[[]]
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Mequinol is a drug used in combination with the drug tretinoin in the treatment of liver spots. .Mequinol used alone and in higher doses is used as a topical drug for medical depigmentation.

Chemistry

It is the monomethyl ether of hydroquinone, and an isomer of guaiacol.

Uses

A combination of mequinol 2% (depigmentation agent) & tretinoin 0.01% (topical retinoid) is commonly used in treating solar lentigines (liver spots & age spots). Exactly how it works is unknown, but this compound is used along with a total skin care and sunlight avoidance program. This compound may also be used for other conditions as determined by one's dermatologist. Methoxyphenol is a depigmentation agent, like Monobenzone (benzyloxyphenol), it is the active ingredient in some depigmenting creams and ointments. A formulation of 20% 4-methoxyphenol ointment causes depigmentation in animal tissue.

Lower dosages of topical mequinol and the Q-switched Ruby Laser have been used to depigment normal skin in vitiligo patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo.

References

fa:مکوئینول nl:4-methoxyfenol