4-Dimethylaminophenol
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Not to be confused with 4-Dimethylaminopyridine.
| 4-Dimethylaminophenol | |
|---|---|
| File:4-Dimethylaminophenol.svg | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 619-60-3 |
| PubChem | 22174 |
| ChemSpider | 20816 |
| SMILES | Script error: No such module "collapsible list". |
| InChI | Script error: No such module "collapsible list". |
| InChI key | JVVRCYWZTJLJSG-UHFFFAOYAU |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C8H11NO |
| Molar mass | 137.179 g/mol |
| Boiling point |
165 °C (0.040 bar) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
4-Dimethylaminophenol (abbreviated in medical practice as DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO.
Uses
4-Dimethylaminophenol has been used as an antidote for cyanide poisoning.[1]
It works by generating methemoglobin. [2]
This is suitable as an emergency treatment only; treatment must be followed up with sodium thiosulfate or cobalamin.
In an animal model, it has shown effectiveness when given intramuscularly.[3]
See also
References
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- ↑ Vick JA, Von Bredow JD (1996). "Effectiveness of intramuscularly administered cyanide antidotes on methemoglobin formation and survival". J Appl Toxicol. 16 (6): 509–16. doi:10.1002/(SICI)1099-1263(199611)16:6<509::AID-JAT382>3.0.CO;2-V. PMID 8956097.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
