Etamivan

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Etamivan
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Systematic (IUPAC) name
N,N-diethyl-4-hydroxy-3-methoxybenzamide
Identifiers
CAS Number 304-84-7
ATC code R07AB04 (WHO)
PubChem CID 9363
Chemical data
Formula C12H17NO3
Molar mass 223.268 g/mol[[Script error: No such module "String".]]
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Etamivan (INN) or ethamivan (USAN), trade name Analepticon, is a respiratory stimulant drug[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose[2] and chronic obstructive pulmonary disease,[3] but has now largely fallen into disuse.


References

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  1. Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
  2. Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
  3. Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.