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• Oerlikon 35 mm twin cannon
  ...netrated the rear equipment bay area of the aircraft and fractured the aft reaction control air pipe. On decelerating to the hover during the recovery, this ca ...inexplicably traversed 90-degrees to the left, breaking through the safety mechanisms, and fired only a 1/8th second long burst, striking all of the soldiers loc
  17 KB (2,537 words) - 20:08, 2 July 2010
• Lidocaine
  ...action of [[2,6-xylidine]] with [[chloroacetyl chloride]], followed by the reaction with [[diethylamine]]:<ref>{{cite journal | journal = [[J. Chem. Ed.]] | vo ...ref name="novartis">{{cite journal |author= Catterall WA |title= Molecular mechanisms of gating and drug block of sodium channels |journal= Novartis Found Symp |
  15 KB (2,006 words) - 15:41, 27 September 2010
• Chloroquine
  ...=Uhlemann AC, Krishna S |title=Antimalarial multi-drug resistance in Asia: mechanisms and assessment |journal=Curr. Top. Microbiol. Immunol. |volume=295 |issue= At the doses used for prevention of malaria, [[adverse drug reaction|side-effects]] include gastrointestinal problems such as [[Abdominal pain|s
  16 KB (2,187 words) - 15:41, 27 September 2010
• Dexamethasone
  ...hemotherapy]] are given Dexamethasone to counteract certain [[Adverse drug reaction|side-effects]] of their antitumor treatment. Dexamethasone can augment the ...|title=Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder |journal=J Clin Endocrinol Met
  18 KB (2,498 words) - 15:41, 27 September 2010
• Praziquantel
  ...or may be destroyed by host immune reaction ([[phagocytosis]]). Additional mechanisms including focal disintegrations and disturbances of oviposition (laying of ...ontents of the parasites as they are killed and the consequent host immune reaction. The heavier the parasite burden, the heavier and more frequent the side ef
  12 KB (1,580 words) - 15:42, 27 September 2010
• Chloramphenicol
  ...usually reversible, and [[aplastic anemia]], which is [[idiosyncratic drug reaction|idiosyncratic]] (rare, unpredictable, and unrelated to dose) and generally The most serious [[adverse drug reaction|side effect]] of chloramphenicol treatment is [[aplastic anaemia]].<ref nam
  29 KB (3,876 words) - 15:42, 27 September 2010
• Metronidazole
  ...st=DiRita |editor4-first=Terence |editor4-last=Dermody |title=Schaechter's mechanisms of microbial disease |publisher=Lippincott Williams & Wilkins |location=Hag Common [[adverse drug reaction]]s (≥1% of patients) associated with [[systemic]] metronidazole therapy i
  19 KB (2,528 words) - 15:43, 27 September 2010
• Vancomycin
  ...o tailor non-ribosomal peptide products-new clues about the structures and mechanisms of modifying enzymes |journal=Mol Biosyst |volume=4 |issue=5 |pages=387–9 ...ve serine is involved in covalent substrate [[amino acid]] binding at each reaction center of gramicidin S synthetase |journal=J. Biol. Chem. |volume=266 |issu
  31 KB (4,198 words) - 15:43, 27 September 2010
• Clofazimine
  ...has a marked anti-inflammatory effect and is given to control the leprosy reaction, [[erythema]] nodosum leprosum (ENL). (From AMA Drug Evaluations Annual, 19 ...r">Arbiser JL, Moschella SL. Clofazimine: a review of its medical uses and mechanisms of action. J Am Acad Dermatol. 1995 Feb;32(2 Pt 1):241-7.</ref><ref name="M
  12 KB (1,651 words) - 15:43, 27 September 2010
• Rifampicin
  ...r J. "Bacterial RNA-Polymerase - Rifampin as Antimycobacterial." Molecular Mechanisms of Drug Action. 2nd ed. Bristol, PA: Taylor Francis, 1994. pp. 40-41.</ref> The most serious [[Adverse drug reaction|adverse effect]] is related to rifampicin's [[hepatotoxicity]], and patient
  18 KB (2,471 words) - 15:43, 27 September 2010
• Flucytosine
  ===Mechanisms of action=== Two major mechanisms of action have been elucidated:
  10 KB (1,394 words) - 15:44, 27 September 2010
• Aciclovir
  To date, resistance to aciclovir has not been clinically significant. Mechanisms of resistance in HSV include deficient viral thymidine kinase; and mutation Common [[adverse drug reaction]]s (≥1% of patients) associated with systemic acyclovir therapy (oral or
  14 KB (1,878 words) - 15:44, 27 September 2010
• Ciprofloxacin
  ...exposes the patient to an unacceptable risk of suffering a severe adverse reaction.<ref>{{cite journal |pmid=9071245 |year=1997 |month=March |author=Hueston, ...debate as to whether or not this DNA damage is to be considered one of the mechanisms of action concerning the severe adverse reactions experienced by some patie
  88 KB (11,930 words) - 15:46, 27 September 2010
• Metformin
  When prescribed appropriately, metformin causes few [[adverse drug reaction|adverse effects]]—the most common is gastrointestinal upset—and, unlike The most common [[adverse drug reaction|adverse effect]] of metformin is gastrointestinal upset, including [[diarrh
  66 KB (8,976 words) - 15:47, 27 September 2010
• Valproic acid
  ...d in recent years.<ref>{{cite journal | author = Rosenberg G | title = The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest ...s the [[voltage-gated sodium channel]]s and T-type calcium channels. These mechanisms make valproic acid a broad spectrum anticonvulsant drug.
  25 KB (3,328 words) - 15:47, 27 September 2010
• Activated carbon
  ...e a very large [[surface area]] available for [[adsorption]] or [[chemical reaction]]s.<ref>[http://www.activated-carbon.com/1-3.html "Properties of Activated Mechanisms of action:
  41 KB (5,738 words) - 15:47, 27 September 2010
• Aspirin
  The main [[adverse drug reaction|undesirable side effects]] of aspirin are [[gastrointestinal]] [[gastric ul ...th a [[sodium]] salt of salicylic acid ([[sodium salicylate]]). A vigorous reaction ensued, and the resulting melt soon solidified.<ref name=gerhardt>{{de icon
  78 KB (10,918 words) - 15:52, 27 September 2010
• Phenoxymethylpenicillin
  ...t some susceptible organisms, particularly [[Gram-negative bacteria]]. The mechanisms and patterns of [[Antibiotic resistance|resistance]] to phenoxymethylpenici ...and [[black hairy tongue]]. A previous [[hypersensitivity|hypersensitivity reaction]] to ''any'' [[penicillin]] is a [[contraindication]].<ref name="DailyMed"/
  5 KB (612 words) - 14:08, 6 July 2010
• Hydrochlorothiazide
  ...easing blood return to the heart and thus [[cardiac output]] and, by other mechanisms, is believed to lower [[peripheral vascular resistance]]. Hydrochlorothiazi Please Note - you may experience an allergic reaction to this medication if you are allergic to sulfa drugs.
  5 KB (655 words) - 15:48, 27 September 2010
• Dopamine
  The level of extracellular dopamine is modulated by two mechanisms, tonic and phasic dopamine transmission. Tonic dopamine transmission occurs ...es inhibit the [[re-uptake]] of dopamine; however, they influence separate mechanisms of action. Cocaine is a [[dopamine transporter]] and [[norepinephrine trans
  48 KB (6,470 words) - 15:48, 27 September 2010

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