Search results

• Quinine
  ...r the early treatment of moderately severe malaria in children: randomised clinical trial | journal=Brit Med J | volume=332 | issue=7549 | pages=1055&ndash;57 ...nent.<ref>{{cite journal | doi=10.1038/clpt.1994.32 | author=Department of Clinical Pharmacology, Huddinge University Hospital, Sweden | title=The concentratio
  27 KB (3,844 words) - 16:41, 27 September 2010
• Chloroquine
  ...ificant therapeutic value as an anti-malarial drug. It was introduced into clinical practice in 1947 for the prophylactic treatment of malaria.<ref>http://www. * Chloroquine is in clinical trials as an investigational [[antiretroviral]] in humans with [[AIDS|HIV-1
  16 KB (2,187 words) - 16:41, 27 September 2010
• Acetylcysteine
  ==Clinical use== ...pmid = 17371789 | issue = 7}}</ref> suggest that the prior pharmacokinetic studies of N-acetylcysteine did not include [[Acetylation]] as a reason for the low
  28 KB (3,682 words) - 16:42, 27 September 2010
• Naloxone
  <!--Clinical data--> ...].<ref>{{cite book|last1=Roberts|first1=James R.|title=Roberts and Hedges' clinical procedures in emergency medicine|date=2014|publisher=Elsevier Health Scienc
  33 KB (4,541 words) - 10:57, 17 June 2016
• Phenytoin
  ...he end of its patent life, and partially due to mixed results from various studies. Following almost 200 studies of 11 anti-seizure drugs, the FDA has also warned of an increased suicide r
  12 KB (1,686 words) - 16:42, 27 September 2010
• Levamisole
  ==Clinical use== ...[[fluorouracil]] to treat [[colon cancer]]. There is no good evidence from clinical trials that its addition to fluorouracil therapy benefits patients with col
  10 KB (1,350 words) - 16:42, 27 September 2010
• Praziquantel
  ...antel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of p ...l.<ref>{{cite journal |author=Quinn DI, Day RO |title=Drug interactions of clinical importance. An updated guide |journal=Drug Saf |volume=12 |issue=6 |pages=3
  12 KB (1,580 words) - 16:42, 27 September 2010
• Clindamycin
  ...and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgaris |journal=Clin Ther |volu
  25 KB (3,261 words) - 14:17, 11 September 2010
• Chloramphenicol
  <ref>[http://www.jbc.org/content/238/7/2498.full.pdf Studies on the Mechanism of Action of Chloramphenicol ] July 1963. The Journal of B ...as a single intramuscular injection. The dose is repeated if there is no clinical response after 48 hours. A single injection costs approximately [[United S
  29 KB (3,876 words) - 16:42, 27 September 2010
• Doxycycline
  ...her JL, Hull DS, Davis LS |title=Ocular rosacea. Signs, symptoms, and tear studies before and after treatment with doxycycline |journal=Arch Dermatol |volume= ...ff A, Massung RF, Christensson B |title=Human granulocytic ehrlichiosis--a clinical case in Scandinavia |journal=Scand. J. Infect. Dis. |volume=33 |issue=1 |pa
  20 KB (2,578 words) - 16:43, 27 September 2010
• Metronidazole
  ...irth defects. Those studies are nowadays considered flawed and more recent studies "do not support a significant increased risk for birth defects or other adv ...ment.<ref name="AMH2006" /> However, the mechanism of this reaction in the clinical setting has recently been questioned by some authors,<ref name="Williams200
  19 KB (2,528 words) - 16:43, 27 September 2010
• Nitrofurantoin
  ...re mutually antagonistic ''in vitro''. It is not known whether this is of clinical significance, but the combination should be avoided. ...or=Richards WA, ''et al.'' | title=Nitrofurantoin: Clinical and laboratory studies in urinary tract infections | journal=Arch Intern Med | year=1955 | volume=
  12 KB (1,576 words) - 16:43, 27 September 2010
• Co-trimoxazole
  ...ite journal|author=Kremers P, Duvivier J, Heusghem C|title=Pharmacokinetic studies of co-trimoxazole in man after single and repeated doses|journal=J Clin Pha ==Clinical indications==
  10 KB (1,346 words) - 16:43, 27 September 2010
• Vancomycin
  ==Clinical use== |title=Serum vancomycin concentrations: reappraisal of their clinical value
  31 KB (4,198 words) - 16:43, 27 September 2010
• Clofazimine
  ...olerate the effects of [[Dapsone]] for Tuberculosis.<ref name="ReferenceA">Clinical Microbiology Made Ridiculously Simple</ref> ...researcher named Chang identified its effectiveness against leprosy. After clinical trials in Nigeria and elsewhere during the 1960s, some sponsored by the Swi
  12 KB (1,651 words) - 16:43, 27 September 2010
• Pyrazinamide
  ...Organisation|WHO]] recommend its use in pregnancy; and there is extensive clinical experience to show that it is safe. In the U.S., pyrazinamide is not used | title = Clinical and molecular analysis of patients with renal hypouricemia in Japan-influen
  12 KB (1,557 words) - 16:44, 27 September 2010
• Amphotericin B
  ...|title=Antileishmanial activity, pharmacokinetics and tissue distribution studies of mannose-grafted amphotericin B lipid nanospheres |journal=J Drug Target ...d Richard T. liposomal formulation, structure, mechanism of action and pre-clinical experience. Journal of Antimicrobial Chemotherapy (2002) 49, 21-30</ref> Th
  13 KB (1,785 words) - 16:44, 27 September 2010
• Flucytosine
  ...Guchelaar HJ, Dankert J |title=Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions |journal=J. A ...rains of ''[[Candida (genus)|Candida]]'' and ''[[Cryptococcus]]''. Limited studies demonstrate that flucytosine may be of value against infections with ''[[Sp
  10 KB (1,394 words) - 16:44, 27 September 2010
• Emtricitabine
  ...e analyses of plasma HIV RNA levels and CD4 cell counts in two Phase III [[clinical trial]]s of Emtriva of 48 weeks duration. ...er being evaluated as a potential treatment for chronic hepatitis B. These studies are ongoing.
  5 KB (667 words) - 16:44, 27 September 2010
• Tenofovir
  ...s. There are no study results demonstrating the effect of tenofovir on the clinical progression of HIV. | title = Additional Studies Needed to Assess Effectiveness of Tenofovir for Prevention
  6 KB (871 words) - 16:45, 27 September 2010
• Nevirapine
  ...|author= Patel SS, Benfield P |title=New drug profile: nevirapine |journal=Clinical Immunotherapeutics |volume=6|issue=4|pages=307–317 |year=1996 |month=Oct ==Clinical efficacy==
  15 KB (2,090 words) - 16:45, 27 September 2010
• Lopinavir
  ...Kaletra formulation has also been used successfully as monotherapy in some studies.<ref>[http://www.aidsmap.com/en/news/4140714E-EFE1-45FD-9E77-E230D787542E.a ...observed with lopinavir/ritonavir are [[diarrhea]] and [[nausea]]. In key clinical trials, moderate or severe diarrhea occurred in up to 27% of patients, and
  8 KB (1,109 words) - 16:45, 27 September 2010
• Nelfinavir
  ...c Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo|journal= Clinical Cancer Research |volume=13|pages=5183–5194|year=2007|doi=10.1158/1078-043 ...]] or [[radiation therapy]]. It might take several years for most of these studies to be completed and their results published.
  8 KB (1,160 words) - 16:45, 27 September 2010
• Ribavirin
  ...children. However, its efficacy has been called into question by multiple studies, and most institutions no longer use it.{{Fact|date=December 2008}} It is s ...") has been sold for use against [[influenza]].{{Fact|date=December 2008}} Studies have been mixed,<ref name="pmid3293527">{{cite journal |author=Bernstein DI
  23 KB (3,222 words) - 16:45, 27 September 2010
• Ketamine
  ...rrison">{{Cite journal|author=Harrison NL, Simmonds MA |title=Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral corte ...=Jansen|first=Karl|publisher=Multidisciplinary Association for Psychedelic Studies|isbn=0966001931|year=2001|page=38}}</ref> Ketamine is a keto-amine, so name
  69 KB (9,697 words) - 21:01, 24 September 2010
• Ciprofloxacin
  ...lume=308 |issue=6941 |page=1437 |issn=0959-8138 |pmc=2540361 |journal=BMJ (Clinical research ed.) |first1=PM |first2=AP |first3=MP |author1=Donaldson, Pm |auth ...ial Pathogen and Immunologic Drug Products - Summary of Clinical Review of Studies Submitted in Response to a Pediatric Written Request |url=http://www.fda.go
  88 KB (11,930 words) - 16:46, 27 September 2010
• Sodium thiopental
  24 KB (3,339 words) - 16:46, 27 September 2010
• Tenofovir/emtricitabine
  ...tive measure if taken daily or weekly leading up to exposure, though human clinical trials are ongoing [http://www.sfgate.com/cgi-bin/article.cgi?f=/n/a/2006/0 ==Clinical Studies==
  3 KB (396 words) - 15:07, 6 July 2010
• Methylene blue
  }}</ref> especially due to its low price. Several clinical trials are in progress, trying to find a suitable drug combination. Initial ...hylene blue difficult to test in traditional placebo-controlled [[clinical studies]].<ref>{{Cite web
  27 KB (3,650 words) - 16:46, 27 September 2010
• Azithromycin
  ...], [[chlamydia infection|chlamydia]], [[gonorrhea]] and cervicitis. Recent studies have also indicated it to be effective against late-onset [[asthma]], but t ...ue=10 | pages=1264&ndash;71 | pmid=17051490 | doi=10.1086/508175 | journal=Clinical infectious diseases : an official publication of the Infectious Diseases So
  15 KB (2,008 words) - 16:46, 27 September 2010
• Metformin
  ...laborating Centre for Chronic Conditions | title=Type 2 diabetes: national clinical guideline for management in primary and secondary care (update) | location= ...in people, and in 1957, French physician Jean Sterne published the first [[clinical trial]] of metformin as a treatment for diabetes. It was introduced to the
  66 KB (8,976 words) - 16:47, 27 September 2010
• Valproic acid
  '''Valproic acid''' ('''VPA''') is a [[chemical compound]] that has found clinical use as an [[anticonvulsant]] and [[mood stabilizer|mood-stabilizing]] [[med ...s and bipolar disorder.<ref>Henry T.R. (2003). The History of Valproate in Clinical Neuroscience. ''Psychopharmacology bulletin'' 37 (Suppl 2):5-16</ref>
  25 KB (3,328 words) - 16:47, 27 September 2010
• Fluoxetine
  .../generic/fluoxetine_cp.htm | title = Prozac Pharmacology, Pharmacokinetics,Studies, Metabolism | year = 2007 | accessdate = 2007-04-14 | publisher = RxList.co ...treatment of major depression: results of a placebo-controlled, randomized clinical trial |journal=J Clin Psychopharmacol |volume=20 |issue=4 |pages=423–7 |y
  52 KB (7,168 words) - 16:47, 27 September 2010
• Aspirin
  ...yocardial infarction (the AFTER study): a multicentre unblinded randomised clinical trial|journal = BMJ| volume = 313|issue = 7070|pages = 1429–1431|publishe ...Mortality, 1918%u20131919 Pharmacology, Pathology, and Historic Evidence. Clinical Infectious Diseases, 2009; DOI: 10.1086/606060</ref> Aspirin's profitabilit
  78 KB (10,918 words) - 16:52, 27 September 2010
• Suramin
  ...are no active clinical trials (as of April 1, 2008). Completed and closed clinical trials are listed here: [http://www.cancer.gov/search/ResultsClinicalTrials ...="pmid678497">{{cite journal |author=Anderson J, Fuglsang H |title=Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suram
  7 KB (906 words) - 16:47, 27 September 2010
• Phenoxymethylpenicillin
  ...y continue oral treatment with phenoxymethylpenicillin once a satisfactory clinical response has been obtained.<ref name="Martindale"/>
  5 KB (612 words) - 15:08, 6 July 2010
• Atenolol
  ...ry-care/ | date=2006-06-30 | publisher=[[National Institute for Health and Clinical Excellence]] | accessdate=2009-02-03}}</ref> ...e been contraindicated when a person carries a diagnosis of asthma, recent studies have revealed that at moderate doses selective B blockers such as Atenolol
  12 KB (1,720 words) - 16:48, 27 September 2010
• Digoxin
  ...51/2/251}}</ref>. This negatively chronotropic effect is important for its clinical use in different arrhythmias (see below). ==Clinical use==
  19 KB (2,738 words) - 16:48, 27 September 2010
• Furosemide
  ==Clinical use in humans== ...three times are permanently barred from racing (for their own protection). Clinical trials followed, and by decade's end, racing commissions in some states beg
  12 KB (1,678 words) - 16:48, 27 September 2010
• Simvastatin
  ...s as well, simvastatin was the first statin drug to be used extensively in clinical practice. ...; most studies involve simvastatin as the study drug. The most influential studies were the [[Scandinavian Simvastatin Survival Study]] (4S) and the [[Heart p
  14 KB (1,967 words) - 16:48, 27 September 2010
• Dopamine
  ...muli]] that become [[Classical conditioning|associated]] with them. Recent studies indicate that [[aggression]] may also stimulate the release of dopamine in ==== Animal studies ====
  48 KB (6,470 words) - 16:48, 27 September 2010
• Azathioprine
  ...i-rejection regime, until [[ciclosporin|cyclosporine]] was introduced into clinical practice (also by Calne) in 1978. ...odroffe R, Yao G, Meads C, Bayliss S, Ready A, Raftery J, Taylor R | title=Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transpl
  11 KB (1,410 words) - 16:49, 27 September 2010
• Salbutamol
  ==Clinical use== Clinical studies show no compelling evidence that salbutamol and other beta 2 agonists can i
  15 KB (2,005 words) - 16:49, 27 September 2010
• Metoclopramide
  ==Clinical use== ...s an aid in gastrointestinal [[radiology]] by increasing transit in barium studies, and as an aid in difficult small intestinal intubation. It is also used in
  11 KB (1,453 words) - 16:49, 27 September 2010
• Cortisol
  ...l levels have been observed in connection with abnormal [[ACTH]] levels, [[clinical depression]], [[stress (psychology)|psychological stress]], and such physio ...e on the transport of water, sodium, and glucose in the jejunum. Perfusion studies in normal subjects and patients with coeliac disease |journal=Scand. J. Gas
  41 KB (5,644 words) - 16:50, 27 September 2010
• Ibuprofen
  ...ev |url=http://www.fasebj.org/cgi/content/full/19/12/1592 }}</ref> Further studies are needed to confirm the results before ibuprofen can be recommended for t ...TJ. | title=Acute poisoning due to non-steroidal anti-inflammatory drugs. Clinical features and management. | journal= Med Toxicol | year=1986 | pages=12–31
  29 KB (3,955 words) - 22:17, 21 September 2010
• Nitrous oxide
  ...being engineered and produced already in 1794, the way was now paved for [[clinical trial]]s, which began when [[Thomas Beddoes]] in 1798 established the ''"Pn ...Illicit drugs">{{cite web |url=http://www.druglibrary.org/schaffer/Library/studies/cu/CU43.html|author=Brecher EM|title=Consumers Union Report on Licit and Il
  61 KB (8,728 words) - 16:50, 27 September 2010
• Mercury (element)
  ...to mercury thermometers and sphygmomanometers being largely phased out in clinical environments in favor of [[alcohol]]-filled, digital, or [[thermistor]]-bas ...mercury|author = National Research Council (U.S.) - Board on Environmental Studies and Toxicology| publisher = National Academies Press|year = 2000|isbn = 978
  69 KB (10,077 words) - 21:35, 20 September 2010
• Zidovudine
  ...cers were caused by retroviruses, but this knowledge was of limited use in clinical settings due to a lack of drugs that were effective against them. The devel ...M198909143211106 | author=Yarchoan R, Mitsuya H, Myers C, Broder S | title=Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related di
  21 KB (3,049 words) - 16:51, 27 September 2010
• Morphine
  In clinical medicine, morphine is regarded as the gold standard, or benchmark, of analg ...=http://books.google.com/?id=MtOiLVWBn8cC&pg=PA20|page=20|title=Molecular, clinical and environmental toxicology|author=Andreas Luch|publisher=Springer|year=20
  87 KB (12,376 words) - 16:51, 27 September 2010

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