Asoprisnil

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Asoprisnil
File:Asoprisnil.png
Systematic (IUPAC) name
rel-4-[(8R,11S,13R,14R,17R)-17-Methoxy-17-

(methoxymethyl)-13-methyl-3-oxo- 2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-

1H-cyclopenta[a]phenanthren-11-yl]benzaldehyde oxime
Identifiers
CAS Number 199396-76-4
ATC code none
PubChem CID 9577221
ChemSpider 7851660
Chemical data
Formula C28H35NO4
Molar mass 449.582 g/mol[[Script error: No such module "String".]]
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Asoprisnil (J867) is an investigational selective progesterone receptor modulator developed by Schering and TAP Pharmaceutical Products, tested for treatment of progesterone sensitive myomata.[1]

In 2005, Phase III trials were discontinued due to endometrial changes in patients. It is uncertain whether asoprisnil will be marketed.[2]

References

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  1. DeManno D, Elger W, Garg R; et al. (2003). "Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy". Steroids. 68 (10-13): 1019–32. doi:10.1016/j.steroids.2003.09.008. PMID 14667995. 
  2. Schering Interim Report Q1-3 2005