Asoprisnil
From Self-sufficiency
File:Asoprisnil.png | |
Systematic (IUPAC) name | |
---|---|
rel-4-[(8R,11S,13R,14R,17R)-17-Methoxy-17-
(methoxymethyl)-13-methyl-3-oxo- 2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro- 1H-cyclopenta[a]phenanthren-11-yl]benzaldehyde oxime | |
Identifiers | |
CAS Number | 199396-76-4 |
ATC code | none |
PubChem | CID 9577221 |
ChemSpider | 7851660 |
Chemical data | |
Formula | C28H35NO4 |
Molar mass | 449.582 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
Asoprisnil (J867) is an investigational selective progesterone receptor modulator developed by Schering and TAP Pharmaceutical Products, tested for treatment of progesterone sensitive myomata.[1]
In 2005, Phase III trials were discontinued due to endometrial changes in patients. It is uncertain whether asoprisnil will be marketed.[2]
References
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- ↑ DeManno D, Elger W, Garg R; et al. (2003). "Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy". Steroids. 68 (10-13): 1019–32. doi:10.1016/j.steroids.2003.09.008. PMID 14667995.
- ↑ Schering Interim Report Q1-3 2005
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