Izonsteride
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File:Izonsteride-structure.png | |
Systematic (IUPAC) name | |
---|---|
(4aR,10bR)-8-[(4-ethyl-1,3-benzothiazol-2-yl)sulfanyl]-4,10b-dimethyl-1,4,4a,5,6,10b-hexahydrobenzo[f]quinolin-3(2H)-one | |
Clinical data | |
Routes of administration | Oral |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | 176975-26-1 |
ATC code | none |
PubChem | CID 172988 |
ChemSpider | 151061 |
Chemical data | |
Formula | C24H26N2OS2 |
Molar mass | 422.61 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
Izonsteride (LY-320,236) is a selective inhibitor of the 5α-redcutase, with dual effects on both the type I and type II isoforms of the enzyme.[1] It was under development by Eli Lilly and Fujisawa for the treatment of benign prostatic hyperplasia (BPH) but was never marketed.[2] Izonsteride may also be useful in the treatment of male pattern baldness (MPB).[1]
See also
References
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- ↑ 1.0 1.1 Chang, Chawnshang (2002). Androgens and androgen receptor : mechanisms, functions, and clinical application. Boston: Kluwer Academic Publishers. ISBN 1-4020-7188-4.
- ↑ "Present and future pharmacotherapy for benign prostatic hyperplasia".
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- 2Fix
- 5-alpha-reductase inhibitors
- Benzothiazoles
- Lactams
- Benzoquinolines