Korotkoff are the sounds that medical personnel listen for when they are taking blood pressure using a non-invasive procedure. They are named after Dr. Nikolai Korotkoff, a Russian physician who described them in 1905, when he was working at the Imperial Medical Academy in St. Petersburg.
The sounds heard during measurement of blood pressure are not the same as the heart sounds 'lub' and 'dub' that are due to the closing of the hearts valves. If a stethoscope is placed over the brachial artery in the antecubital fossa in a normal person (without arterial disease), no sound should be audible. As the heart beats, these pulses are transmitted smoothly via laminar (non-turbulent) blood flow throughout the arteries and no sound is produced. Also, if the cuff of a sphygmomanometer is placed around a patient's upper arm and inflated to a pressure above the patient's systolic blood pressure, there will be no sound audible. This is because the pressure in the cuff is high enough such that it completely occludes the blood flow. It is similar to a flexible tube or pipe with fluid in it that is being pinched shut.
If the pressure is dropped to a level equal to that of the patient's systolic blood pressure, the first Korotkoff sound will be heard. As the pressure in the cuff is the same as the pressure produced by the heart, some blood will be able to pass through the upper arm when the pressure in the artery rises during systole. This blood flows in spurts as the pressure in the artery rises above the pressure in the cuff and then drops back down beyond the cuffed region, resulting in turbulence that results in audible sound.
As the pressure in the cuff is allowed to fall further, thumping sounds continue to be heard as long as the pressure in the cuff is between the systolic and diastolic pressures, as the arterial pressure keeps on rising above and dropping back below the pressure in the cuff.
Eventually, as the pressure in the cuff drops further, the sounds change in quality, then become muted, then disappear altogether. As the pressure in the cuff drops below the diastolic blood pressure, the cuff no longer provides any restriction to blood flow allowing the blood flow to become smooth again with no turbulence and thus produce no further audible sound.
The five Korotkoff sounds
Korotkoff actually described five types of sounds:
- The first Korotkoff sound is the snapping sound first heard at the systolic pressure. Clear tapping, repetitive sounds for at least two consecutive beats is considered the systolic pressure.
- The second sounds are the murmurs heard for most of the area between the systolic and diastolic pressures.
- The third = A loud, crisp tapping sound.
- The fourth sound, at pressures within 10 mmHg above the diastolic blood pressure, were described as "thumping" and "muting".
- The fifth Korotkoff sound is silence as the cuff pressure drops below the diastolic blood pressure. The disappearance of sound is considered diastolic blood pressure -- two mm Hg above the last sound heard.
The second and third Korotkoff sounds have no known clinical significance. 
Systolic and diastolic blood pressure
Traditionally, the systolic blood pressure is taken to be the pressure at which the first Korotkoff sound is first heard and the diastolic blood pressure is the pressure at which the fourth Korotkoff sound is just barely audible. However, there has recently been a move towards the use of the fifth Korotkoff sound (i.e. silence) as the diastolic blood pressure, as this has been felt to be more reproducible.
For paediatrics however, auscultation of the fourth Korotkoff sound is now the guiding indicator of diastolic pressure. 
The time average of the first Korotkoff sound represents a reliable pressure marker of Systole of the heart. The time average of the fourth Korotkoff sound represents a reliable pressure marker of Diastole of the heart.
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- editor Julie Munden (2006), Best Practices: Evidence-Based Nursing Procedures (2nd ed.), Lippincott Williams, ISBN 158255532X
- Patricia A. Potter, Anne Griffin Perry ; section editors, Amy Hall, Patricia A. Stockert. (2009), Potter and Perry's fundamentals of nursing (7th ed.), Mosby, Inc., ISBN 9780323048286
bg:Тон на Коротков