Sergliflozin etabonate

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Sergliflozin etabonate
File:Sergliflozin etabonate.svg
Systematic (IUPAC) name
2-(4-methoxybenzyl)phenyl 6-O-(ethoxycarbonyl)-β-D-glucopyranoside
Clinical data
Routes of
administration		 Oral
Identifiers
CAS Number 408504-26-7
ATC code none
PubChem CID 9824918
Chemical data
Formula C23H28O9
Molar mass 448.463 g/mol[[Script error: No such module "String".]]
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Sergliflozin etabonate (INN/USAN,[1][2] codenamed GW869682X) is an investigational anti-diabetic drug being developed by GlaxoSmithKline. It did not undergo further development after phase II.[citation needed]

Method of action

Sergliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter causes blood glucose to be eliminated through the urine.[3][4]

References

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Insulin
Meglitinides/"glinides"
Analogs/other insulins
Other
Amylin analog
SGLT2 inhibitors
Canagliflozin† · Dapagliflozin† · Remogliflozin† · Sergliflozin†
Other


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  1. ↑ World Health Organization (2008). "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 59" (PDF). WHO Drug Information. 22 (1): 66. 
  2. ↑ "Statement on a nonproprietary name adopted by the USAN council: Sergliflozin etabonate" (PDF). American Medical Association. Retrieved 2008-08-10. 
  3. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  4. ↑ Prous Science: Molecule of the Month November 2007
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