Cloprednol

From Self-sufficiency

Cloprednol
Systematic (IUPAC) name
File:Cloprednol.png
(9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
Identifiers
CAS Number	5251-34-3
ATC code	H02AB14 (WHO)
PubChem	CID 10023463
ChemSpider	4447592
Chemical data
Formula	C₂₁H₂₅ClO₅
Molar mass	392.873[[Script error: No such module "String".]]
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Cloprednol is a glucocorticoid.

It is synthetic.^[1]

It has been investigated for use in asthma.^[2]

References

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Mineralocorticoids
(3-one, 4-ene,
no FG at 16)

Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)

Pregnene	CORTISONE
Pregnenedione (+20-one)	HYDROCORTISONE/CORTISOL^# (Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate) · Budesonide · Ciclesonide · Deflazacort · Medrysone · Tixocortol · HALOGENATED AT 6: Cloprednol · HALOGENATED, WITH FG AT 16: Halcinonide
Pregnadiene (+1-ene)	Rimexolone · HALOGENATED, WITH FG AT 16: Flunisolide · Triamcinolone · Amcinonide · Fluocinolone acetonide (Fluocinonide)
Pregnadienediol (+21-hydroxy)	Prednisone (Meprednisone) · HALOGENATED AT 9: Fluorometholone · HALOGENATED, WITH FG AT 16: Fluocortolone (Clocortolone, Diflucortolone, Fluocortin) · Desoximetasone
Pregnadienetriol (+11-hydroxy)	Prednisolone^# (Methylprednisolone, Methylprednisolone aceponate, Prednicarbate, Prednylidene) · Desonide · HALOGENATED: Fluprednisolone (Difluprednate, Fluperolone) · HALOGENATED, WITH FG AT 16: Dexamethasone^# · Betamethasone (Clobetasol, Clobetasone, Diflorasone, Halometasone, Ulobetasol) · Beclometasone · Paramethasone · Alclometasone · Fluclorolone · Flumetasone · Fluprednidene
Pregnatriene (+2-ene)	Cortivazol
Androstene	HALOGENATED, WITH FG AT 16: Fluticasone (Fluticasone propionate, Fluticasone furoate)
Other/ungrouped	HALOGENATED: Loteprednol · HALOGENATED, WITH FG AT 16: Fludroxycortide · Formocortal · Mometasone furoate

Synthesis modifiers

v t e Corticosteroids for systemic use (H02)
Mineralocorticoids	Aldosterone - Fludrocortisone - Desoxycortone
Glucocorticoids	Betamethasone - Dexamethasone - Fluocortolone - Methylprednisolone - Paramethasone - Prednisolone - Prednisone - Triamcinolone - Hydrocortisone - Cortisone - Prednylidene - Rimexolone - Deflazacort - Cloprednol - Meprednisone - Cortivazol
Anticorticosteroids	Trilostane

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↑ Ortega E, Rodriguez C, Strand LJ, Bessler S, Segre E (1976). "Metabolic effects of cloprednol-a new systemic corticosteroid". J Clin Pharmacol. 16 (2-3): 122–8. PMID 1254734.
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