|Systematic (IUPAC) name|
Copolymer of N'-(2-aminoethyl)-N-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine and 2-(chloromethyl)oxirane
|ATC code||C10AC02 (WHO)|
|Molar mass||281.8260 g/mol[[Script error: No such module "String".]]|
|Script error: No such module "collapsible list".|
Colestipol is a bile acid sequestrant. It works in the gut trapping bile salts, and preventing them from being reabsorbed.
This leads to decreased enterohepatic recirculation of bile salts, increased synthesis of new bile salts by the liver, decreased liver cholesterol, increased LDL receptor expression, and decreasing LDL in blood.
- Increases in VLDL and TAG synthesis
- Gastrointestinal tract disturbances
- Malabsorption of lipid soluble vitamins (A,D,E,K) and lipid soluble drugs
Colestipol is contraindicated in hypertriglyceridemia.
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