Disopyramide

Disopyramide
	File:Disopyramide.svg
	File:Disopramide.png
Systematic (IUPAC) name
	4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
Clinical data
Pregnancy; category	AU: B2 ; US: C (Risk not ruled out) ; ;
Routes of; administration	Oral, intravenous
Legal status
Legal status	UK: POM (Prescription only) ; US: ℞-only ;
Pharmacokinetic data
Bioavailability	High
Protein binding	50% to 65%; (concentration-dependent)
Metabolism	Hepatic (CYP3A4-mediated)
Biological half-life	6.7 hours (range 4 to 10 hours)
Excretion	Renal (80%)
Identifiers
CAS Number	3737-09-5
ATC code	C01BA03 (WHO)
PubChem	CID 3114
DrugBank	APRD00507
ChemSpider	3002
Chemical data
Formula	C21H29N3O
Molar mass	339.475 g/mol[[Script error: No such module "String".]]
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Disopyramide (INN, trade names Norpace and Rythmodan) is an antiarrhythmic medication. It is a Class Ia antiarrhythmic (sodium channel blocker) used in the treatment of ventricular tachycardias. It has no effect on alpha or beta adrenergic receptors. It resembles Quinidine but it has a marked anti-muscarinic effect on the heart, for this reason, it is not considered as a drug of 1st choice. It is also used in ventricular arrhythmia and supraventricular arrhythmia that might follow myocardial infarctions.