Ajmaline

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Ajmaline
File:Ajmaline.svg
Systematic (IUPAC) name
(17R,21β)-ajmalan- 17,21-diol
OR
(1R,9R,10S,13R,14R,16S,18S)- 13-ethyl- 8-methyl- 8,15-diazahexacyclo [14.2.1.01,9.02,7.010,15.012,17] nonadeca- 2(7),3,5-triene- 14,18-diol
Identifiers
CAS Number 4360-12-7
ATC code C01BA05 (WHO)
PubChem CID 20367
DrugBank DB01426
ChemSpider 10469368
Chemical data
Formula C20H26N2O2
Molar mass 326.433 g/mol[[Script error: No such module "String".]]
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Ajmaline is a class Ia antiarrhythmic agent. It is often used to bring out typical findings of ST elevations in patients suspected of having Brugada syndrome.

The compound was first isolated by Salimuzzaman Siddiqui in 1931 [1] from the roots of Rauwolfia serpentina. He named it ajmaline, after Hakim Ajmal Khan, one of the most illustrious practitioners of Unani medicine in South Asia.[2]

See also

References

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  1. Siddiqui, S.; Siddiqui, R. H. (1931). J. Indian Chem. Soc. 8: 667–80.
  2. Ahmed Nasim Sandilvi (2003), Salimuzzaman Siddiqui: pioneer of scientific research in Pakistan. Daily Dawn. 12 April 2003. Retrieved on 19 July 2007.