|Systematic (IUPAC) name|
|Molar mass||315.453 g/mol[[Script error: No such module "String".]]|
Pamaquine was the first synthetic antimalarial drug.
Pamaquine is effective against the hypnozoites of the relapsing malarias (P. vivax and P. ovale); and unlike primaquine, it is also very effective against the erythrocytic stages of all four human malarias. One small clinical trial of pamaquine as a causal prophylactic was disappointing (whereas primaquine is an extremely effective causal prophylactic).
60 mg once daily for 14–21 days.
When treating Plasmodium vivax, an initial course of chloroquine is unnecessary.
- Plasmochin, plasmoquine, plasmaquine
- Sweeney AW, Blackburn CRB, KH Rieckmann. (1 August 2004). "Short report: The activity of pamaquine, an 8-aminoquinoline drug, against sporozoite-induced infections of Plasmodium vivax (New Guinea strains)". Am J Trop Med Hyg. 71 (2): 187–189. PMID 15306708.