Yttrium (90Y) tacatuzumab tetraxetan
From Self-sufficiency
| File:Y-90 tacatuzumab tetraxetan structure.svg | |
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Template:Infobox drug/mab source |
| Target | α-fetoprotein |
| Identifiers | |
| CAS Number | 500784-58-7 |
| ATC code | none |
| Chemical data | |
| Formula | C6470H9971N1712O2007S4290Y |
| Molar mass | 145 kDa |
Yttrium (90Y) tacatuzumab tetraxetan (trade name AFP-Cide) is a humanized monoclonal antibody intended for the treatment of cancer.[1] The antibody itself, tacatuzumab, is conjugated with a chelator for yttrium-90[2], a radioisotope which destroys the tumour cells.
The chelator ("tetraxetan") is 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. The antibody is attached to one of the four carboxyl groups as an amide, and the other three are carboxylate anions neutralizing the three positive charges of the yttrium ion.
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />
| 40x30px | This monoclonal antibody-related article is a stub. You can help ssf by expanding it. |
Categories:
- Pages with script errors
- Pages with broken file links
- Infobox drug articles with non-default infobox title
- Drugs that are a monoclonal antibody
- Infobox drug tracked parameters
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Chemical articles using a fixed chemical formula
- Drugs not assigned an ATC code
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- 2Fix
- Cancer treatments
- Monoclonal antibody stubs
