Difference between revisions of "Capreomycin"
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{{Antimycobacterials}} | {{Antimycobacterials}} | ||
[[Category:Tuberculosis]] | [[Category:Tuberculosis]] | ||
[[Category:Aminoglycoside antibiotics]] | [[Category:Aminoglycoside antibiotics]] | ||
[[Category:World Health Organization essential medicines]] | [[Category:World Health Organization essential medicines]] | ||
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[[de:Capreomycin]] | [[de:Capreomycin]] | ||
Latest revision as of 15:44, 27 September 2010
| File:Capreomycin IA.svg | |
| File:Capreomycin IB.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide; (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-methyl-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide | |
| Identifiers | |
| CAS Number | 11003-38-6 |
| ATC code | J04AB30 (WHO) |
| PubChem | CID 3032400 |
| DrugBank | APRD00844 |
| Chemical data | |
| Formula | C25H44N14O8 |
| Molar mass | 668.706 g/mol[[Script error: No such module "String".]] |
Capreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for tuberculosis. Adverse effects include nephrotoxicity and 8th cranial nerve toxicity.
The drug should not be given with streptomycin or other drugs that may damage the 8th nerve.
It is a cyclic peptide.[1]
References
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