Lorcainide

Lorcainide

File:Lorcainide.svg
Systematic (IUPAC) name
N-(4-chlorophenyl)-N-(1-isopropylpiperidin-4-yl)-2-phenylacetamide
Pharmacokinetic data
Protein binding	78
Biological half-life	14.3 +/-3.7
Identifiers
CAS Number	59729-31-6
ATC code	C01BC07 (WHO)
PubChem	CID 42884
Chemical data
Formula	C22H27ClN2O
Molar mass	370.915 g/mol[[]]

Lorcainide is a class 1c antiarrhythmic agent. It was discovered at Janssen Pharmaceutica in 1968.

References

• Kesteloot H, Stroobandt R., Clinical experience with lorcainide (R 15 889), a new anti-arrhythmic drug, Arch Int Pharmacodyn Ther. 1977 Dec;230(2):225-34.
• Carmeliet E, Janssen PA, Marsboom R, Van Nueten JM, Xhonneux R., Antiarrhythmic, electrophysiologic and hemodynamic effects of lorcainide, Arch Int Pharmacodyn Ther. 1978 Jan;231(1):104-30.