Ethionamide
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| File:Ethionamide.png | |
| Systematic (IUPAC) name | |
|---|---|
|
2-ethylpyridine-4-carbothioamide | |
| Pharmacokinetic data | |
| Protein binding | Approximately 30% bound to proteins. |
| Biological half-life | 2 to 3 hours |
| Identifiers | |
| CAS Number | 536-33-4 |
| ATC code | J04AD03 (WHO) |
| PubChem | CID 2761171 |
| DrugBank | APRD00961 |
| Chemical data | |
| Formula | C8H10N2S |
| Molar mass | 166.244 g/mol[[Script error: No such module "String".]] |
| (verify) | |
Ethionamide (2-ethylthioisonicotinamide, Trecator SC) is an antibiotic used in the treatment of tuberculosis.
It has been proposed for use in combination with gatifloxacin.[2]
The action may be through disruption of mycolic acid.[3]
Synthesis
Liberman, D.; Rist, N.; Grumbach, F.; Cals, S.; Moyeux, M.; Rouaix, A.; Bull. Soc. Chim. Fr. 1958, 687.
References
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