Etofibrate

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Etofibrate
File:Etofibrate.svg
Systematic (IUPAC) name
2-[(pyridin-3-yl)carbonyloxy]ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
Pharmacokinetic data
Metabolism Hydrolyzed to clofibric acid and niacin
Identifiers
CAS Number 31637-97-5
ATC code C10AB09 (WHO)
PubChem CID 65777
Chemical data
Formula C18H18ClNO5
Molar mass 363.792 g/mol[[Script error: No such module "String".]]
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Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.[1]

References

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GI tract
Liver
Niacin and derivatives (HDL and LDL)
Blood vessels
Combinations
Other

M: MET

mt, a/u/y/n/h, r/g/c/p/i, f/s/l/o, m

au/y/n/h, rgcp/i, f/s/l/o, m, epon

meds(A16, C10),intm(a/u/y/n/h, r/g/c/p/i, f/s/o)


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pt:Etofibrato
  1. ↑ Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CR, Coelho OR, Ramires JA (2001). "Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects". Braz J Med Biol Res. 34 (2): 177–82. doi:10.1590/S0100-879X2001000200004. PMID 11175492.  Free full text
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