ATC code L01

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ATC codes
L Antineoplastic and immunomodulating agents
L01 Antineoplastic agents
L02 Endocrine therapy
L03 Immunostimulants
L04 Immunosuppressants
A • B • C • D • G • H • QI • J • L • M • N • P • R • S • V

ATC code L01 Antineoplastic agents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup L01 is part of the anatomical group L Antineoplastic and immunomodulating agents.^[1]

Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: QL01...^[2] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.

National issues of the ATC classification may include additional codes not present in this list, which follows the WHO version.

Contents

1 L01A Alkylating agents
2 L01B Antimetabolites
3 L01C Plant alkaloids and other natural products
4 L01D Cytotoxic antibiotics and related substances
5 L01X Other antineoplastic agents
6 References

L01A Alkylating agents

L01AA Nitrogen mustard analogues

L01AA01 Cyclophosphamide

L01AA02 Chlorambucil

L01AA03 Melphalan

L01AA05 Chlormethine

L01AA06 Ifosfamide

L01AA07 Trofosfamide

L01AA08 Prednimustine

L01AA09 Bendamustine

L01AB Alkyl sulfonates

L01AB01 Busulfan

L01AB02 Treosulfan

L01AB03 Mannosulfan

L01AC Ethylene imines

L01AC01 Thiotepa

L01AC02 Triaziquone

L01AC03 Carboquone

L01AD Nitrosoureas

L01AD01 Carmustine

L01AD02 Lomustine

L01AD03 Semustine

L01AD04 Streptozocin

L01AD05 Fotemustine

L01AD06 Nimustine

L01AD07 Ranimustine

L01AG Epoxides

L01AG01 Etoglucid

L01AX Other alkylating agents

L01AX01 Mitobronitol

L01AX02 Pipobroman

L01AX03 Temozolomide

L01AX04 Dacarbazine

L01B Antimetabolites

L01BA Folic acid analogues

L01BA01 Methotrexate

L01BA03 Raltitrexed

L01BA04 Pemetrexed

L01BA05 Pralatrexate

L01BB Purine analogues

L01BB02 Mercaptopurine

L01BB03 Tioguanine

L01BB04 Cladribine

L01BB05 Fludarabine

L01BB06 Clofarabine

L01BB07 Nelarabine

L01BC Pyrimidine analogues

L01BC01 Cytarabine

L01BC02 Fluorouracil

L01BC03 Tegafur

L01BC04 Carmofur

L01BC05 Gemcitabine

L01BC06 Capecitabine

L01BC07 Azacitidine

L01BC08 Decitabine

L01BC52 Fluorouracil, combinations

L01BC53 Tegafur, combinations

L01C Plant alkaloids and other natural products

L01CA Vinca alkaloids and analogues

L01CA01 Vinblastine

L01CA02 Vincristine

L01CA03 Vindesine

L01CA04 Vinorelbine

L01CA05 Vinflunine

L01CB Podophyllotoxin derivatives

L01CB01 Etoposide

L01CB02 Teniposide

L01CC Colchicine derivatives

L01CC01 Demecolcine

L01CD Taxanes

L01CD01 Paclitaxel

L01CD02 Docetaxel

L01CD03 Paclitaxel poliglumex

L01CX Other plant alkaloids and natural products

L01CX01 Trabectedin

L01D Cytotoxic antibiotics and related substances

L01DA Actinomycines

L01DA01 Dactinomycin

L01DB Anthracyclines and related substances

L01DB01 Doxorubicin

L01DB02 Daunorubicin

L01DB03 Epirubicin

L01DB04 Aclarubicin

L01DB05 Zorubicin

L01DB06 Idarubicin

L01DB07 Mitoxantrone

L01DB08 Pirarubicin

L01DB09 Valrubicin

L01DC Other cytotoxic antibiotics

L01DC01 Bleomycin

L01DC02 Plicamycin

L01DC03 Mitomycin

L01DC04 Ixabepilone

L01X Other antineoplastic agents

L01XA Platinum compounds

L01XA01 Cisplatin

L01XA02 Carboplatin

L01XA03 Oxaliplatin

L01XA04 Satraplatin

L01XB Methylhydrazines

L01XB01 Procarbazine

L01XC Monoclonal antibodies

L01XC01 Edrecolomab

L01XC02 Rituximab

L01XC03 Trastuzumab

L01XC04 Alemtuzumab

L01XC05 Gemtuzumab

L01XC06 Cetuximab

L01XC07 Bevacizumab

L01XC08 Panitumumab

L01XC09 Catumaxomab

L01XC10 Ofatumumab

L01XD Sensitizers used in photodynamic/radiation therapy

L01XD01 Porfimer sodium

L01XD03 Methyl aminolevulinate

L01XD04 Aminolevulinic acid

L01XD05 Temoporfin

L01XD06 Efaproxiral

L01XE Protein kinase inhibitors

L01XE01 Imatinib

L01XE02 Gefitinib

L01XE03 Erlotinib

L01XE04 Sunitinib

L01XE05 Sorafenib

L01XE06 Dasatinib

L01XE07 Lapatinib

L01XE08 Nilotinib

L01XE09 Temsirolimus

L01XE10 Everolimus

L01XE11 Pazopanib

QL01XE90 Masitinib

QL01XE91 Toceranib

L01XX Other antineoplastic agents

L01XX01 Amsacrine

L01XX02 Asparaginase

L01XX03 Altretamine

L01XX05 Hydroxycarbamide

L01XX07 Lonidamine

L01XX08 Pentostatin

L01XX09 Miltefosine

L01XX10 Masoprocol

L01XX11 Estramustine

L01XX14 Tretinoin

L01XX16 Mitoguazone

L01XX17 Topotecan

L01XX18 Tiazofurine

L01XX19 Irinotecan

L01XX22 Alitretinoin

L01XX23 Mitotane

L01XX24 Pegaspargase

L01XX25 Bexarotene

L01XX27 Arsenic trioxide

L01XX29 Denileukin diftitox

L01XX32 Bortezomib

L01XX33 Celecoxib

L01XX35 Anagrelide

L01XX36 Oblimersen

L01XX37 Sitimagene ceradenovec

L01XX38 Vorinostat

L01XX39 Romidepsin

L01XY Combinations of antineoplastic agents

References

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Intracellular chemotherapeutic agents/antineoplastic agents (L01)

SPs/MIs
(M phase)

Block microtubule assembly	Vinca alkaloids (Vinblastine, Vincristine, Vinflunine, Vindesine, Vinorelbine)
Block microtubule disassembly	Taxanes (Cabazitaxel, Docetaxel, Larotaxel, Ortataxel, Paclitaxel, Tesetaxel) · Epothilones (Ixabepilone)

DNA replication
inhibitor

DNA precursors/
antimetabolites
(S phase)

Folic acid	dihydrofolate reductase inhibitor (Aminopterin, Methotrexate, Pemetrexed, Pralatrexate) · thymidylate synthase inhibitor (Raltitrexed, Pemetrexed)
Purine	adenosine deaminase inhibitor (Pentostatin) halogenated/ribonucleotide reductase inhibitors (Cladribine, Clofarabine, Fludarabine) thiopurine (Thioguanine, Mercaptopurine)
Pyrimidine	thymidylate synthase inhibitor (Fluorouracil, Capecitabine, Tegafur, Carmofur, Floxuridine) DNA polymerase inhibitor (Cytarabine) ribonucleotide reductase inhibitor (Gemcitabine) hypomethylating agent (Azacitidine, Decitabine)
Deoxyribonucleotide	ribonucleotide reductase inhibitor (Hydroxycarbamide)

Topoisomerase inhibitors
(S phase)

I	Camptotheca (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan)
II	Podophyllum (Etoposide, Teniposide)
II+Intercalation	Anthracyclines (Aclarubicin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Amrubicin, Pirarubicin, Valrubicin, Zorubicin) · Anthracenediones (Mitoxantrone, Pixantrone)

Crosslinking of DNA
(CCNS)

Alkylating	Nitrogen mustards: Mechlorethamine · Cyclophosphamide (Ifosfamide, Trofosfamide) · Chlorambucil (Melphalan, Prednimustine) · Bendamustine · Uramustine · Estramustine Nitrosoureas: Carmustine · Lomustine (Semustine) · Fotemustine · Nimustine · Ranimustine · Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan, Treosulfan) Aziridines: Carboquone · ThioTEPA · Triaziquone · Triethylenemelamine
Alkylating-like	Platinum (Carboplatin, Cisplatin, Nedaplatin, Oxaliplatin, Triplatin tetranitrate, Satraplatin)
Nonclassical	Hydrazines (Procarbazine) · Triazenes (Dacarbazine, Temozolomide) · Altretamine · Mitobronitol
Intercalation	Streptomyces (Actinomycin, Bleomycin, Mitomycin, Plicamycin)

Photosensitizers/PDT

Aminolevulinic acid/Methyl aminolevulinate · Efaproxiral · Porphyrin derivatives (Porfimer sodium, Talaporfin, Temoporfin, Verteporfin)

Other

Enzyme inhibitors	FI (Tipifarnib) · CDK inhibitors (Alvocidib, Seliciclib) · PrI (Bortezomib) · PhI (Anagrelide) · IMPDI (Tiazofurine) · LI (Masoprocol) · PARP inhibitor (Olaparib) · HDAC (Vorinostat, Romidepsin)
Receptor antagonists	ERA (Atrasentan) · retinoid X receptor (Bexarotene) · sex steroid (Testolactone)
Other/ungrouped	Amsacrine · Trabectedin · retinoids (Alitretinoin, Tretinoin) · Arsenic trioxide · asparagine depleters (Asparaginase/Pegaspargase) · Celecoxib · Demecolcine · Elesclomol · Elsamitrucin · Etoglucid · Lonidamine · Lucanthone · Mitoguazone · Mitotane · Oblimersen · mTOR inhibitors (Everolimus, Temsirolimus)

tmsp, onco, mrkr

tumr, epon, para

ca:Codi ATC L01

cs:ATC kód L01 es:Anexo:Código ATC L01 hu:ATC L01 – Daganatellenes szerek pl:ATC (L01) ro:Cod ATC L01 sv:ATC-kod L01: Cytostatiska/cytotoxiska medel

th:ATC รหัส L01

↑ "ATC Index". WHO Collaborating Centre for Drug Statistics Methodology.
↑ "ATCvet Index". WHO Collaborating Centre for Drug Statistics Methodology.

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