Talaporfin
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| File:Talaporfin.png | |
| Systematic (IUPAC) name | |
|---|---|
|
N-{[(2S,3S)-7-carboxy-3-(2-carboxyethyl)-12-ethyl-2,8,13,18-tetramethyl-17-vinyl-2,3-dihydroporphyrin-5-yl]acetyl}-L-aspartic acid | |
| Clinical data | |
| Routes of administration | IV |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number |
110230-98-3 220201-34-3 (sodium salt) |
| ATC code | none |
| PubChem | CID 5486799 |
| Chemical data | |
| Formula | C38H41N5O9 |
| Molar mass | 711.76 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorine e6, NPe6, or LS11) is a photosensitizer used in photodynamic therapy (PDT).
It absorbs red light at 664nm normally provided by a laser tuned to this wavelength.[1]
It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin.[2]
References
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| 40px | This antineoplastic or immunomodulatory drug article is a stub. You can help ssf by expanding it. |
- ↑ http://journals.lww.com/jto/Fulltext/2006/06000/Photodynamic_Therapy__PDT__for_Lung_Cancers.18.aspx "Photodynamic Therapy (PDT) for Lung Cancers" 2006
- ↑ http://meeting.ascopubs.org/cgi/content/abstract/24/18_suppl/7229 "Photodynamic therapy using Laserphyrin for centrally located early stage lung cancer" 2006
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