Enocitabine

From Self-sufficiency

Revision as of 20:44, 29 July 2010 by PotatoBot (Talk) (Stub sorting and placement of stub template(s): antineoplastic-drug-stub)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Enocitabine
Systematic (IUPAC) name
320px
N-[1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide
Clinical data
Routes of administration	IV
Legal status
Legal status	℞ (Prescription only)
Identifiers
CAS Number	55726-47-1
ATC code	none
PubChem	CID 71734
Chemical data
Formula	C₃₁H₅₅N₃O₆
Molar mass	565.78 g/mol[[Script error: No such module "String".]]
Script error: No such module "collapsible list".

Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Enocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.

Sunrabin contains the emulsifier HCO-60, which can cause allergic reactions.^[1]

References

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />

Block microtubule assembly	Vinca alkaloids (Vinblastine, Vincristine, Vinflunine, Vindesine, Vinorelbine)
Block microtubule disassembly	Taxanes (Cabazitaxel, Docetaxel, Larotaxel, Ortataxel, Paclitaxel, Tesetaxel) · Epothilones (Ixabepilone)

Folic acid	dihydrofolate reductase inhibitor (Aminopterin, Methotrexate, Pemetrexed, Pralatrexate) · thymidylate synthase inhibitor (Raltitrexed, Pemetrexed)
Purine	adenosine deaminase inhibitor (Pentostatin) halogenated/ribonucleotide reductase inhibitors (Cladribine, Clofarabine, Fludarabine) thiopurine (Thioguanine, Mercaptopurine)
Pyrimidine	thymidylate synthase inhibitor (Fluorouracil, Capecitabine, Tegafur, Carmofur, Floxuridine) DNA polymerase inhibitor (Cytarabine) ribonucleotide reductase inhibitor (Gemcitabine) hypomethylating agent (Azacitidine, Decitabine)
Deoxyribonucleotide	ribonucleotide reductase inhibitor (Hydroxycarbamide)

I	Camptotheca (Camptothecin, Topotecan, Irinotecan, Rubitecan, Belotecan)
II	Podophyllum (Etoposide, Teniposide)
II+Intercalation	Anthracyclines (Aclarubicin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Amrubicin, Pirarubicin, Valrubicin, Zorubicin) · Anthracenediones (Mitoxantrone, Pixantrone)

Alkylating	Nitrogen mustards: Mechlorethamine · Cyclophosphamide (Ifosfamide, Trofosfamide) · Chlorambucil (Melphalan, Prednimustine) · Bendamustine · Uramustine · Estramustine Nitrosoureas: Carmustine · Lomustine (Semustine) · Fotemustine · Nimustine · Ranimustine · Streptozocin Alkyl sulfonates: Busulfan (Mannosulfan, Treosulfan) Aziridines: Carboquone · ThioTEPA · Triaziquone · Triethylenemelamine
Alkylating-like	Platinum (Carboplatin, Cisplatin, Nedaplatin, Oxaliplatin, Triplatin tetranitrate, Satraplatin)
Nonclassical	Hydrazines (Procarbazine) · Triazenes (Dacarbazine, Temozolomide) · Altretamine · Mitobronitol
Intercalation	Streptomyces (Actinomycin, Bleomycin, Mitomycin, Plicamycin)

Other

Enzyme inhibitors	FI (Tipifarnib) · CDK inhibitors (Alvocidib, Seliciclib) · PrI (Bortezomib) · PhI (Anagrelide) · IMPDI (Tiazofurine) · LI (Masoprocol) · PARP inhibitor (Olaparib) · HDAC (Vorinostat, Romidepsin)
Receptor antagonists	ERA (Atrasentan) · retinoid X receptor (Bexarotene) · sex steroid (Testolactone)
Other/ungrouped	Amsacrine · Trabectedin · retinoids (Alitretinoin, Tretinoin) · Arsenic trioxide · asparagine depleters (Asparaginase/Pegaspargase) · Celecoxib · Demecolcine · Elesclomol · Elsamitrucin · Etoglucid · Lonidamine · Lucanthone · Mitoguazone · Mitotane · Oblimersen · mTOR inhibitors (Everolimus, Temsirolimus)