Afloqualone
From Self-sufficiency
140px | |
Systematic (IUPAC) name | |
---|---|
6-amino- 2-(fluoromethyl)- 3-(2-methylphenyl) quinazolin- 4-one | |
Identifiers | |
CAS Number | 56287-74-2 |
ATC code | none |
PubChem | CID 2040 |
ChemSpider | 1960 |
Chemical data | |
Formula | C16H14FN3O |
Molar mass | 283.3[[Script error: No such module "String".]] |
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Afloqualone (Arofuto) is an analogue of methaqualone developed in the 1980s in Japan. It has sedative and muscle relaxant effects,[1] and has had some clinical use, although it causes photosensitization as a side effect which can cause skin problems such as dermatitis.[2]
See also
References
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- ↑ Ochiai T, Ishida R. Pharmacological studies on 6-amino- 2-fluoromethyl- 3-(O-tolyl)- 4(3H)- quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Japanese Journal of Pharmacology. 1982 Jun;32(3):427-38.
- ↑ Ishikawa T, Kamide R, Niimura M. Photoleukomelanodermatitis (Kobori) induced by afloqualone. Journal of Dermatology. 1994 Jun;21(6):430-3.
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