|Systematic (IUPAC) name|
6-amino- 2-(fluoromethyl)- 3-(2-methylphenyl) quinazolin- 4-one
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Afloqualone (Arofuto) is an analogue of methaqualone developed in the 1980s in Japan. It has sedative and muscle relaxant effects, and has had some clinical use, although it causes photosensitization as a side effect which can cause skin problems such as dermatitis.
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- Ochiai T, Ishida R. Pharmacological studies on 6-amino- 2-fluoromethyl- 3-(O-tolyl)- 4(3H)- quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Japanese Journal of Pharmacology. 1982 Jun;32(3):427-38.
- Ishikawa T, Kamide R, Niimura M. Photoleukomelanodermatitis (Kobori) induced by afloqualone. Journal of Dermatology. 1994 Jun;21(6):430-3.